从“五体”角度探讨肌少症的防治策略  

Discussion on pathogenesis and prevention strategy of sarcopenia based on the five body constituents

作　　者：薛泰骑 郭弋凡 刘武 周一 张梦 张宁[1] XUE Taiqi;GUO Yifan;LIU Wu;ZHOU Yi;ZHANG Meng;ZHANG Ning(Nephrology and Endocrinology Department,Wangjing Hospital,China Academy of Chinese Medical Sciences,Beijing 100070,China;Graduate School,Beijing University of Chinese Medicine,Beijing 100029,China)

机构地区：[1]中国中医科学院望京医院肾病内分泌科,北京100070 [2]北京中医药大学研究生院,北京100029

出　　处：《陕西中医》2025年第2期220-224,共5页Shaanxi Journal of Traditional Chinese Medicine

基　　金：国家自然科学基金资助面上项目(81973801);中国中医科学院科技创新工程(CI2021A01609);中国中医科学院望京医院自主选题专项课题(QJYY-ZZXT-2022-13);北京中医药大学教育教学改革专项课题(XJYZ22021)。

摘　　要：肌少症是一种与多种慢性疾病相关的退行性疾病,表现为肌肉质量、力量和功能的减退。本文从“五体”角度探讨皮、肉、脉、筋、骨及其对应脏腑与肌肉质量、肌肉力量及肌肉功能之间的关系,为临床治疗提供借鉴思路。在五体理论指导下,五脏外应五体,五脏充盛,五体健壮,则肌肉丰满,力量充盛,功能强健。若五脏受损,五体失养,则表现为肌肉瘦削、力量下降和功能减退。因此临床中可根据累及五体及对应脏腑进行针对性治疗:肌少症早期肌肉质量下降宜健脾益气增肌肉;肌少症期肌肉力量下降宜疏肝养血强力量;晚期肌肉功能衰退宜补肾填精益功能,治疗过程中配合益心安神养五体、补肺固卫护五体,达到增加肌肉质量、提高肌肉力量、改善肌肉功能的目的。Sarcopenia is a degenerative disease associated with aging,characterized by a decrease in muscle mass,muscle strength,as well as muscle function.This article explores the relationship between“skin,vessel,muscle,tendon,and bone”with the five internal organs.Their relationship with muscle mass,muscle strength,and muscle function from the perspective of the“Five body constituents”provides reference ideas for clinical management.Under the guidance of the“Five body constituents”theory,the five body constituents are the external manifestation of the five organs.If the five organs are in the harmonious status,the five body constituents would be bouncing strong,which manifests externally as the muscles.If the five body constituents lose nourishment due to the impairment of the five organs,the mass of muscle,the strength of muscle,and the function of the muscle would decrease.Therefore,targeted treatment can be carried out based on the involvement of five body constituents and five organs in clinical practice:strengthening the spleen and replenishing qi to increase muscle mass in the early stage of sarcopenia;soothing the liver and nourishing blood to increase the strength of muscle during the period of sarcopenia;tonifying the kidney and supplementing essence during the end-stage of sarcopenia.It is important to nourish the heart,calm the mind,nourish the five body constituents,as well as strengthen the lungs and protect the five body constituents to increase muscle mass,improve muscle strength,and improve muscle function.

关 键 词：肌少症 五体 五脏 防治策略 健脾 益气 

分 类 号：R685[医药卫生—骨科学]