Are we prepared for the next pandemic:Monitor on increasing human and animal H5N1 avian influenza infection  

作　　者：Qing Wang Yanxia Sun Zhongjie Li Weizhong Yang Luzhao Feng 

机构地区：[1]School of Population Medicine&Public Health,Chinese Academy of Medical Sciences/Peking Union Medical College,Key Laboratory of Pathogen Infection Prevention and Control,Peking Union Medical College,Ministry of Education,State Key Laboratory of Respiratory Health and Multimorbidity,Beijing 100730,China

出　　处：《Chinese Medical Journal》2024年第23期2776-2781,共6页中华医学杂志(英文版)

基　　金：supported by grants from the Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences(Nos.2022-I2M-CoV19-006,2021-I2M-1-044);the Science&Technology Fundamental Resources Investigation Program(No.2023FY100600).

摘　　要：Human infection with highly pathogenic avian influenza(HPAI)caused by certain strains of avian influenza A viruses,such as H5N1 and H7N9,results in severe acute respiratory disease with a high mortality rate,among which the former is pathogenic to birds.[1]In recent years,HPAI H5 has spread globally,causing human infections.The first reported case of bovine H5N1 infection,which was subsequently transmitted to humans,garnered significant international attention.Drawing on the historical influenza pandemic experience and biological characteristics of the virus,under specific conditions,such as reassortment with human and swine influenza viruses,avian influenza viruses(AIV)may achieve efficient human-to-human transmission,potentially leading to a global pandemic.Here,we aimed to review the historical trends of H5N1 avian influenza infections in humans and the recent developments in epidemiological situations,evaluate the transmission risk of H5N1 avian influenza,and propose avian influenza control recommendations for public health decision-making.

关 键 词：H5N1 AVIAN H7N9 

分 类 号：S85[农业科学—兽医学]