基于数据挖掘的余尚贞治疗原发性高血压用药规律研究  

Research on Treatment of Essential Hypertension by YU Shangzhen Based on Data Mining

作　　者：黄卓 向蕾 余尚贞 HUANG Zhuo;XIANG Lei;YU Shangzhen(Guangzhou Zengcheng District Hospital of Traditional Chinese Medicine,Guangzhou 510632,China;Jiangmen Hospital of Traditional Chinese Medicine Affiliated to Jinan University,Jiangmen 529000,China)

机构地区：[1]广州市增城区中医医院,广州510632 [2]暨南大学附属江门中医院,广东江门529000

出　　处：《江西中医药大学学报》2025年第1期25-29,36,共6页Journal of Jiangxi University of Chinese Medicine

基　　金：广东省名中医余尚贞传承工作室建设项目(粤中医办函[2017]17号)。

摘　　要：目的:通过数据挖掘总结余尚贞治疗原发性高血压(EH)的用药规律及临证经验。方法:收集2017年9月—2020年9月就诊于暨南大学附属江门中医院余尚贞名中医工作室的EH病例,建立余尚贞治疗EH门诊医案数据库,使用IBM SPSS 24.0、IBM Modeler 18.0等软件,采用关联规则、聚类分析等方法,挖掘其用药特点及组方规律。结果:共纳入病例136例、处方408张,包含中药132味、核心中药21味,得出7个核心药组。结论:余尚贞认为,治疗EH的要义在于调和气血,主张从太阴、阳明论治,常选用补虚药、清热药、解表药等,药味多属甘、苦、辛,擅用补益肝肾、抑木扶土、活血利水等法,注重调畅情志、天人相应、随症加减。Objective:To explore the empirical methods of YU Shangzhen's treatment of essential hypertension through data mining.Methods:We collected cases of essential hypertension who attended Yu Shangzhen Famous Traditional Chinese Medicine Workshop of Jiangmen Hospital of Traditional Chinese Medicine affiliated to Jinan University from September 2017 to September 2020,established a database of outpatient medical cases of YU Shangzhen's treatment of essential hypertension,and used software such as IBM SPSS 24.0 and IBM Modeler 18.0,and employed methods such as association rules and cluster analysis to mine the characteristics of medication and the law of prescription organization.Results:A total of 136 cases and 408 prescriptions were included,including 132 flavors of traditional Chinese medicines and 21 core traditional Chinese medicines,resulting in 7 core drug groups.Conclusion:YU Shangzhen believes that the key to treating essential hypertension lies in the regulation of qi and blood,and advocates treating it from the theory of Taiyin-Yangming,often choosing medicines for tonifying deficiency,clearing heat and relieving epidemics,etc.,and the flavors of the medicines are mostly"sweet""bitter"and"pungent",and they are good at tonifying and benefiting the body."It specializes in tonifying the liver and kidneys,suppressing wood and supporting earth,promoting blood circulation and inducing diuresis,etc.It focuses on regulating the emotions,corresponding to Heaven and Man,and adding and subtracting according to the symptoms.

关 键 词：原发性高血压 中医药治疗 余尚贞 用药规律 数据挖掘 

分 类 号：R255.3[医药卫生—中医内科学]