综合干预对冠心病患者介入治疗后桡动脉闭塞的预防价值  

Preventive value of comprehensive intervention on radial artery occlusion after interventional therapy in patients with coronary heart disease

作　　者：马涛[1] 马健[1] 吴志胜[1] 王宝珠[2] Ma Tao;Ma Jian;Wu Zhisheng;Wang Baozhu(Cardiovascular Disease Interventional Diagnosis and Treatment Center,the First Affiliated Hospital of Xinjiang Medical University,Urumqi 830000,Xinjiang,China;Coronary Care Unit,Cardiovascular Disease Center,the First Affiliated Hospital of Xinjiang Medical University,Urumqi 830000,Xinjiang,China)

机构地区：[1]新疆医科大学第一附属医院心血管病中心介入诊疗中心,新疆乌鲁木齐830000 [2]新疆医科大学第一附属医院心血管病中心重症监护室,新疆乌鲁木齐830000

出　　处：《血管与腔内血管外科杂志》2024年第12期1477-1480,1501,共5页Journal of Vascular and Endovascular Surgery

基　　金：新疆维吾尔自治区重点研发计划项目(2022B03022-5)。

摘　　要：目的探讨综合干预对冠心病患者介入治疗后桡动脉闭塞的预防价值。方法收集2022年3月至2024年2月于新疆医科大学第一附属医院接受冠状动脉介入治疗的249例冠心病患者的临床资料,按照干预措施的不同将患者分为观察组(n=131,围手术期接受了针对桡动脉闭塞预防的综合干预)和对照组(n=118,术中主要使用硝酸甘油预防桡动脉闭塞)。主要观察指标为术后24 h内桡动脉闭塞的发生率,次要观察指标为穿刺点出血、术后6 h拇指肿胀的发生率以及术后6 h拇指指尖脉氧饱和度﹤95%的比例。结果两组患者的冠心病特点和介入治疗主要指标比较,差异均无统计学意义(P﹥0.05)。观察组患者术后24 h内桡动脉闭塞的发生率、术后6 h拇指指尖脉氧饱和度﹤95%的比例均低于对照组患者,差异均有统计学意义(P﹤0.05)。两组患者穿刺点出血、术后6 h拇指肿胀的发生率比较,差异均无统计学意义(P﹥0.05)。结论综合干预可以降低冠心病患者介入治疗后桡动脉闭塞的发生风险,值得临床推广。Objective To investigate the preventive value of comprehensive intervention on radial artery occlusion after interventional therapy in patients with coronary heart disease.Method The clinical data of 249 cases coronary heart disease patients who received coronary artery intervention treatment at the First Affiliated Hospital of Xinjiang Medical University from March 2022 to February 2024 were collected.The patients were divided into observation group(n=131,received comprehensive intervention for radial artery occlusion prevention during the perioperative period)and control group(n=118,mainly used nitroglycerin to prevent radial artery occlusion during surgery)according to different intervention measures.The main outcome measure was the incidence of radial artery occlusion within 24 h after surgery,and the secondary outcome measures were the incidence of bleeding at the puncture site,thumb swelling at 6 h after surgery,and the proportion of thumb fingertip pulse oxygen saturation<95%at 6 h after surgery.Result There were no statistically significant differences in the characteristics of coronary heart disease and the main indicators of interventional therapy between the two groups of patients(P>0.05).The incidence of radial artery occlusion within 24 h after surgery and the proportion of thumb fingertip pulse oxygen saturation<95%at 6 h after surgery in the observation group were lower than those in the control group,and the differences were statistically significant(P<0.05).There were no statistically significant differences in the incidence of bleeding at the puncture site and thumb swelling at 6 h after surgery between the two groups of patients(P>0.05).Conclusion Comprehensive intervention can significantly reduce the risk of radial artery occlusion in patients with coronary heart disease after interventional therapy,and is worthy of clinical promotion.

关 键 词：综合干预 冠心病 介入治疗 桡动脉闭塞 预防 

分 类 号：R543[医药卫生—心血管疾病]