基于“脑-肠轴”探讨针药治疗轻度认知障碍合并便秘的可行性  

Feasibility of acupuncture and medication treatment for mild cognitive impairment combined with constipation based on the "Brain-Gut Axis"

作　　者：申珮华 鲁海 汪洋[2] 陈怡[1] 徐天舒[1] SHEN Peihua;LU Hai;WANG Yang;CHEN Yi;XU Tianshu(Drum Tower Clinical Medical College,Nanjing University of Chinese Medicine,Nanjing 210008;Nanjing Drum Tower Hospital,Nanjing 210008,China)

机构地区：[1]南京中医药大学鼓楼临床医学院,江苏南京210008 [2]南京鼓楼医院,江苏南京210008

出　　处：《临床医学研究与实践》2025年第3期179-182,共4页Clinical Research and Practice

基　　金：国家自然科学基金资助项目(No.82274520)。

摘　　要：轻度认知障碍(MCI)作为阿尔茨海默病的先兆,常合并便秘发生。临床对于认知障碍及便秘的发病机制探讨较多,其中现代医学“脑-肠轴”以及中医理论的“脑-肠相关”与认知障碍合并便秘的发病密切相关。本文基于“脑-肠”理论结合针药治疗认知障碍合并便秘的临床应用,提出以脾胃枢机为关键,脑肠共治的治疗思路,论述针药结合作为治疗手段的可行性,以期为针药结合治疗认知障碍合并便秘提供理论依据。Mild cognitive impairment(MCI),as the early stage of Alzheimer's disease,is often accompanied by constipation.There are many clinical studies on the pathogenesis of cognitive impairment and constipation.Among them,"Brain-Gut Axis"of modern medicine and the"brain-gut correlation"of traditional Chinese medicine theory are closely related to the pathogenesis of cognitive impairment and constipation.Based on the clinical application of"brain-gut"theory combined with acupuncture and medicine in the treatment of cognitive impairment with constipation,this paper puts forward the treatment idea of spleen-stomach pivot as the key and brain-gut co-governance,and discusses the feasibility of acupuncture combined with medicine as a treatment method,in order to provide a theoretical basis for the treatment of cognitive impairment with constipation by acupuncture combined with medicine.

关 键 词：脑-肠轴 认知障碍 便秘 针药结合 共病 

分 类 号：R473[医药卫生—护理学]