儿童斑秃的药物治疗进展  

Research Progress of Drugs in Treating Pediatric Alopecia Areata

作　　者：余丽娟 任韵清 YU Lijuan;REN Yunqing(Department of Dermatology,Children’s Hospital,Zhejiang University School of Medicine,National Clinical Research Center for Child Health,Hangzhou 310052,China)

机构地区：[1]浙江大学医学院附属儿童医院皮肤科,国家儿童健康与疾病临床医学研究中心,杭州310052

出　　处：《中国现代应用药学》2025年第1期153-157,共5页Chinese Journal of Modern Applied Pharmacy

摘　　要：斑秃是一种常见的毛囊自身免疫性疾病,主要表现为圆形或椭圆形脱发斑,严重者可进展为全秃或普秃。斑秃会影响外貌,从而影响患儿的心理健康,故及时控制病情至关重要。外用糖皮质激素仍是治疗儿童斑秃的一线方案,对于外用糖皮质激素治疗无效者或病情进展较快者,可考虑采用其他治疗手段。近年来,Janus激酶抑制剂、生物制剂等给治疗带来了新的希望。本文主要对近年来国内外儿童斑秃的药物治疗进行综述。Alopecia areata is a common autoimmune disorder affecting hair follicles,primarily manifested as circular or oval patches of hair loss.In severe cases,it can progress to alopecia totalis or alopecia universalis.Alopecia areata impacts appearance,thereby affecting the mental health of affected children,making timely disease control crucial.Topical corticosteroids remain the first-line treatment for alopecia areata in children.For those who do not respond to topical corticosteroids or whose condition progresses rapidly,other therapeutic options should be considered.In recent years,Janus kinase inhibitors and biologics have brought new hope for treatment.This article primarily reviews the pharmacological treatments for alopecia areata in children,both domestically and internationally,in recent years.

关 键 词：儿童 斑秃 药物 治疗 

分 类 号：R969.3[医药卫生—药理学]