Numerical simulations of a two-strain dengue model to investigate the efficacy of the deployment of Wolbachia-carrying mosquitoes and vaccination for reducing the incidence of dengue infections  

作　　者：Meksianis Z.Ndii Nursanti Anggriani Bertha S.Djahi Sanubari Tansah Tresna Fatuh Inayaturohmat 

机构地区：[1]Department of Mathematics,The University of Nusa Cendana,Kupang-NTT,Indonesia [2]Deparment of Mathematics,Padjadjaran University,Jatinangor-Jawa Barat,Indonesia [3]Department of Computer Science,The University of Nusa Cendana,Kupang-NTT,Indonesia

出　　处：《Journal of Biosafety and Biosecurity》2024年第4期244-251,共8页生物安全和生物安保杂志(英文)

基　　金：funded by Kementerian Pendidikan,Kebudayaan,Riset dan Teknologi 2023,with contract No.216/UN15.19/SP2H/LT/2023.

摘　　要：This study investigated the usefulness of a two-serotype dengue mathematical model to gain insights into the effects of antibody-dependent enhancement and temperature on dengue transmission dynamics in the presence of vaccination and Wolbachia-carrying mosquitoes.In particular,the effects of temperature on the mosquito death and maturation rates in secondary infections were examined.A deterministic mathematical model was formulated and analysed to address this problem.The results suggest that controlling the population of aquatic mosquitoes is appropriate for reducing the incidence of secondary infections.Furthermore,the wAu Wolbachia strain was more effective in reducing secondary infections.

关 键 词：DENGUE Mathematical model WOLBACHIA VACCINATION Antibody-dependent enhancement 

分 类 号：R51[医药卫生—内科学]