Lensless fiber endomicroscopy in biomedicine  

作　　者：Jiawei Sun Robert Kuschmierz Ori Katz Nektarios Koukourakis Juergen W.Czarske 

机构地区：[1]Competence Center for Biomedical Computational Laser Systems(BIOLAS),TU Dresden,Dresden 01069,Germany [2]Shanghai Artificial Intelligence Laboratory,Longwen Road 129,Xuhui District,Shanghai 200232,China [3]Laboratory of Measurement and Sensor System Technique(MST),TU Dresden,Helmholtzstrasse 18,Dresden 01069,Germany [4]Else Kroner Fresenius Center for digital Heath,TU Dresden,Dresden 01062,Germany [5]Institute of Applied Physics,The Hebrew University of Jerusalem,Jerusalem,Israel [6]Cluster of Excellence Physics of Life,TU Dresden,Dresden 01062,Germany [7]Institute of Applied Physics,TU Dresden,Dresden 01062,Germany

出　　处：《PhotoniX》2024年第1期402-410,共9页智汇光学(英文)

基　　金：organized by Projekt DEAL.German Research Foundation(DFG)grant CZ55/40,CZ55/47;European Research Council(ERC)Horizon 2020 research and innovation program(grant no.101002406);Shanghai Artificial Intelligence Laboratory,National Key R&D Program of China(2022ZD0160100);Else Kroner Fresenius Center for digital Heath(EKFZ)and Competence Center for Biomedical Computational Laser Systems(BIOLAS).

摘　　要：Lensless fiber endomicroscopy,an emergent paradigm shift for minimally-invasive microscopic optical imaging and targeted light delivery,holds transformative potential,especially in biomedicine.Leveraging holographic detection and physical or computational wavefront correction,it enables three-dimensional imaging in an unprecedentedly small footprint,which is crucial for various applications such as brain surgery.This perspective reviews the recent breakthroughs,highlighting potential emerging applications,and pinpointing gaps between innovation and real-world applications.As the research in this realm accelerates,the novel breakthroughs and existing frontiers highlighted in this perspective can be used as guidelines for researchers joining this exciting domain.

关 键 词：Lensless endomicroscope Biomedical imaging Multimode fibers Multicore fibers Translation to real-world applications 

分 类 号：O43[机械工程—光学工程]