LC contact lens sensor for ultrasensitive intraocular pressure monitoring  

作　　者：Hongbin An Xian Wang Zhikang Liao Liang Zhang Hui Zhao Yingyun Yang Jizhou Song Yinji Ma 

机构地区：[1]Laboratory of Flexible Electronics Technology,Tsinghua University(THU),Beijing,100084,P.R.China [2]Department of Engineering Mechanics,Zhejiang University,Hangzhou,310027,P.R.China [3]Institute of Flexible Electronics Technology of THU,Jiaxing,314000,P.R.China [4]Department of Military Traffic Injury Prevention and Control,Daping Hospital,Army Medical University,Chongqing,400042,P.R.China [5]Department of Gastroenterology,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing,100084,P.R.China [6]AML,Department of Engineering Mechanics,Tsinghua University,Beijing,100084,P.R.China

出　　处：《npj Flexible Electronics》2024年第1期357-370,共14页npj-柔性电子(英文)

基　　金：the support from the National Basic Research Program of China(Grant No.2023YFB3609002);the National Natural Science Foundation of China(Grant Nos.12225209 and U21A20502);the Tsinghua Precision Medicine Foundation(Grant No.100010104);the capital health research and development of special(Grant No.2022-4-4019);the Natural Science Foundation of Zhejiang Province(Grant No.LQ23H18007).

摘　　要：Twenty-four hours continuous intraocular pressure(IOP)monitoring is beneficial for glaucoma care.Contact lens sensors using LC technology can achieve non-invasive continuous IOP measuring around the clock and are relatively simple in principle and structure,thus dominating the mainstream.Among them,stretchable inductive LC contact lens sensors constructed with liquid metal have advantages in signal quality as well as wearing comfort,but currently its sensitivity is slightly insufficient.Here,we propose an LC sensor that constructed with liquid metal to form the stretchable inductance and capacitance further.The capacitive plate and inductive coil can response to IOP changes simultaneously,thus able to enhance the sensitivity in principle.We modeled the sensing mechanism and conducted design,fabrication,as well as various tests.The device exhibits good characteristics,including reliability,good signal quality,etc.Especially,it has a threefold increase in sensitivity,exceeding the current state-of-the-art contact lens sensors.

关 键 词：INDUCTIVE EXCEEDING slightly 

分 类 号：TP2[自动化与计算机技术—检测技术与自动化装置]