病原微生物检测在儿童细菌性腹泻中的诊断价值  

Diagnostic Value of Pathogenic Microorganism Detection in Children with Bacterial Diarrhea

作　　者：肖春萍 XIAO Chunping(Department of Clinical Laboratory,Ji'an Maternal and Child Health Hospital,Ji'an 343000,Jiangxi,China)

机构地区：[1]吉安市妇幼保健院检验科,江西吉安343000

出　　处：《医学信息》2025年第1期145-148,共4页Journal of Medical Information

摘　　要：目的探讨病原微生物检测在儿童细菌性腹泻中的诊断价值。方法选取2020年1月-2023年8月于吉安市妇幼保健院收治的60例细菌性腹泻患儿作为研究对象,对患儿进行病原微生物检验。记录患儿病原微生物分布情况,统计不同菌种对不同抗菌药的耐药性,并根据患儿的不同年龄记录病原微生物的检出情况。结果60例患儿中共检出病原微生物52株,其中沙门菌占比57.69%(30/52),高于大肠埃希菌、弧菌属及其他菌属(P<0.05);此外,药敏试验结果显示,各类病原微生物对抗菌药物存在不同程度的耐药性,相比之下大肠埃希菌对复方磺胺耐药性、沙门菌对氨苄西林耐药性、弧菌属对头孢唑啉耐药性、其他菌属中的头孢唑啉耐药性要高于其他抗菌药物;另外,2~6岁患儿病原菌检出率为91.43%,高于<2岁患儿的80.00%(P<0.05);夏秋季节病原菌检出率高于春冬季病原菌检出率(P<0.05)。结论对于儿童细菌性腹泻的诊断,临床应用病原微生物检验的效果理想,可有效检测出导致患儿细菌性腹泻的病原菌,以便为临床治疗提供可靠依据,实现临床对症给药治疗。Objective To explore the diagnostic value of pathogenic microorganism detection in children with bacterial diarrhea.Methods A total of 60 children with bacterial diarrhea admitted to Ji'an Maternal and Child Health Hospital from January 2020 to August 2023 were selected as the research objects,and the pathogenic microorganisms of the children were tested.The distribution of pathogenic microorganisms in children was recorded,the resistance of different strains to different antibiotics was counted,and the detection of pathogenic microorganisms was recorded according to the different ages of children.Results A total of 52 strains of pathogenic microorganisms were detected in 60 children,of which Salmonella accounted for 57.69%(30/52),which was higher than that of Escherichia coli,Vibrio and other bacteria(P<0.05).In addition,the results of drug sensitivity test showed that all kinds of pathogenic microorganisms had different degrees of resistance to antimicrobial drugs.In contrast,the resistance of Escherichia coli to compound sulfanilamide,the resistance of Salmonella to ampicillin,the resistance of Vibrio to cefazolin,and the resistance of cefazolin in other bacteria were higher than other antimicrobial drugs.In addition,the detection rate of pathogenic bacteria in children aged 2-6 years was 91.43%,which was higher than 80.00%in children aged<2 years(P<0.05).The detection rate of pathogenic bacteria in summer and autumn was higher than that in spring and winter(P<0.05).Conclusion For the diagnosis of bacterial diarrhea in children,the effect of clinical application of pathogenic microorganism test is ideal,which can effectively detect the pathogenic bacteria leading to bacterial diarrhea in children,so as to provide a reliable basis for clinical treatment and realize clinical symptomatic medication.

关 键 词：病原微生物 细菌性腹泻 药敏试验 

分 类 号：R446.5[医药卫生—诊断学]