Standard:human intestine‑on‑a‑chip  

作　　者：Haitao Liu Yaqing Wang Xu Zhang Min Zhang Peng Wang Jing Shang Zhongqiang Li Likun Gong Jiabin Guo Wei Sun Jingbo Pi Xianliang Li Wei Ding Dianbing Wang Zhongyu Li Jingzhong Zhang Lan Wang Xingchao Geng Ruifu Yang Pingkun Zhou Wanjin Tang Xian’en Zhang Chunying Chen Shengli Yang Jianhua Qin 

机构地区：[1]Division of Biotechnology,Dalian Institute of Chemical Physics,Chinese Academy of Sciences,Dalian,China [2]University of Science and Technology of China,Hefei,China [3]Suzhou Institute for Advanced Research,University of Science and Technology of China,Suzhou,China [4]China Pharmaceutical University,Nanjing,China [5]China National Institute of Standardization,Beijing,China [6]Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai,China [7]Chinese People’s Liberation Army(PLA)Center for Disease Control and Prevention,Beijing,China [8]Tsinghua University,Beijing,China [9]China Medical University,Shenyang,China [10]Department of HBP Surgery,Beijing Chao Yang Hospital,the Capital Medical University,Beijing,China [11]SPH KDL Health Beijing,Shanghai Pharma,Beijing,China [12]Institute of Biophysics,Chinese Academy of Sciences,Beijing,China [13]Dalian Minzu University,Dalian,China [14]Suzhou Institute of Biomedical Engineering and Technology,Chinese Academy of Sciences,Suzhou,China [15]Dalian Xin’en Medical Technology Co.,LTD,Dalian,China [16]National Institutes for Food and Drug Control,Beijing,China [17]Institute of Microbiology and Epidemiology,Academy of Military Medical Sciences,Beijing,China [18]Institute of Radiation Medicine,Chinese Academy of Medical Sciences,Tianjin,China [19]Shenzhen University of Advanced Technology,Shenzhen,China [20]National Center for Nanoscience and Technology,Beijing,China

出　　处：《Cell Regeneration》2024年第1期227-236,共10页细胞再生(英文)

基　　金：National Key R&D Program of China(No.2022YFA1104700)to Zhang X;National Natural Science Foundation of China(No.32171406)to Qin J;Innovation Program of Science and Research from the DICP,CAS(DICP I202435)to Qin J.

摘　　要：Organs-on-chips are microphysiological systems that allow to replicate the key functions of human organs and accel-erate the innovation in life sciences including disease modeling,drug development,and precision medicine.How-ever,due to the lack of standards in their definition,structural design,cell source,model construction,and functional validation,a wide range of translational application of organs-on-chips remains a challenging.“Organs-on-chips:Intestine”is the first group standard on human intestine-on-a-chip in China,jointly agreed and released by the experts from the Chinese Society of Biotechnology on 29th April 2024.This standard specifies the scope,terminology,definitions,technical requirements,detection methods,and quality control in building the human intestinal model on a chip.The publication of this group standard will guide the institutional establishment,acceptance and execution of proper practical protocols and accelerate the international standardization of intestine-on-a-chip for translational applications.

关 键 词：Organs-on-chips Intestine-on-a-chip Microphysiological system STANDARD 

分 类 号：TP3[自动化与计算机技术—计算机科学与技术]