Incidence of active tuberculosis in HIV-infected individuals not receiving universal tuberculosis preventive treatment  

作　　者：Ling Chen Lifan Zhang Leidan Zhang Liyuan Zheng Jia Tang Xiaojing Song Yanling Li Xiaoxia Li Wei Lv Ling Luo Fuping Guo Xinchao Liu Guiren Ruan Huanling Wang Yang Han Taisheng Li Wei Cao 

机构地区：[1]Department of Infectious Diseases,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences&Peking Union Medical College,Beijing 100730,China [2]School of Medicine,Tsinghua University,Beijing 100084,China [3]State Key Laboratory of Complex Severe and Rare Diseases,Peking Union Medical College Hospital,Chinese Academy of Medical Science&Peking Union Medical College,Beijing 100730,China

出　　处：《Chinese Medical Journal》2024年第22期2761-2763,共3页中华医学杂志(英文版)

摘　　要：To the Editor:Tuberculosis(TB)is the leading cause of death in people living with HIV(PLWH)globally.Given the increased risk of TB infection,TB preventive therapy(TPT)is recommended for PLWH to prevent TB activation and to reduce relevant mortality.However,the implementation of TPT remains weak with only 21%of eligible PLWH initiated on TPT globally in 2021,[1]primarily due to the implementation challenges in developing countries.The low completion rate of TPT may be attributed to various reasons,including socio-economic factors,individual behaviors(medication adherence,lack of knowledge,etc.),unstable supply chain of anti-TB drugs,and insufficient understanding of TB treatment guidelines.

关 键 词：TUBERCULOSIS UNSTABLE treatment 

分 类 号：R52[医药卫生—内科学]