Design of a compact beam transport system for laser-driven proton therapy  

作　　者：Yangfan LI Xiaofei SHEN Yilin YAO Bin QIAO 李扬帆;沈晓飞;姚屹林;乔宾(Graduate School of China Academy of Engineering Physics,Beijing 100193,People’s Republic of China;Center for Applied Physics and Technology,HEDPS,and SKLNPT,School of Physics,Peking University,Beijing 100871,People’s Republic of China;Research Center of Laser Fusion,China Academy of Engineering Physics,Mianyang 621000,People’s Republic of China;Collaborative Innovation Center of IFSA(CICIFSA),Shanghai Jiao Tong University,Shanghai 200240,People’s Republic of China;Frontiers Science Center for Nano-optoelectronic,Peking University,Beijing 100094,People’s Republic of China)

机构地区：[1]Graduate School of China Academy of Engineering Physics,Beijing 100193,People’s Republic of China [2]Center for Applied Physics and Technology,HEDPS,and SKLNPT,School of Physics,Peking University,Beijing 100871,People’s Republic of China [3]Research Center of Laser Fusion,China Academy of Engineering Physics,Mianyang 621000,People’s Republic of China [4]Collaborative Innovation Center of IFSA(CICIFSA),Shanghai Jiao Tong University,Shanghai 200240,People’s Republic of China [5]Frontiers Science Center for Nano-optoelectronic,Peking University,Beijing 100094,People’s Republic of China

出　　处：《Plasma Science and Technology》2025年第1期1-6,共6页等离子体科学和技术(英文版)

基　　金：supported by the National Key R&D Program of China(Nos.2022YFA1603200 and 2022YFA1603201);National Natural Science Foundation of China(Nos.12135001,11921006,12475243 and 11825502);Strategic Priority Research Program of CAS(No.XDA25050900);support from the National Natural Science Funds for Distinguished Young Scholar(No.11825502)。

摘　　要：We put forward a new design of a compact beam transport system for intense laser-driven proton therapy,where instead of using conventional pulsed solenoids,our design relies on a helical coil irradiated by a nanosecond laser pulse to generate strong magnetic fields for focusing protons.A pair of dipole magnets and apertures are employed to further filter protons with large divergences and low energies.Our numerical studies combine particle-in-cell simulations for laser-plasma interaction to generate high-energy monoenergetic proton beams,finite element analysis for evaluating the magnetic field distribution inside the coil,and MonteCarlo simulations for beam transport and energy deposition.Our results show that with this design,a spread-out Bragg peak in a range of several centimeters to a deep-seated tumor with a dose of approximately 16.5 cGy and fluctuation around 2% can be achieved.The instantaneous dose rate reaches up to 10^(9)Gy/s,holding the potential for future FLASH radiotherapy research.

关 键 词：intense laser-plasma interaction laser-driven ion acceleration laser-driven proton acceleration PARTICLE-IN-CELL proton radiotherapy 

分 类 号：TN249[电子电信—物理电子学] O53[理学—等离子体物理]