非编码RNAs调控猪胚胎附植和胎盘发育的研究进展  

Research Progress on the Role of non Coding RNA in Pig Embryo Implantation and Placental Development

作　　者：黄慧君 谭宝华 肖丽窈 杨玉铭 洪林君 黄思秀 徐铮 顾婷 HUANG Huijun;TAN Baohua;XIAO Liyao;HONG Linjun;HUANG Sixiu;XU Zheng;GU Ting(College of Animal Science,South China Agricultural University/National Engineering Research Center For Breeding Swine Industry,Guangdong Guangzhou 510642,China)

机构地区：[1]华南农业大学动物科学学院,国家生猪种业工程技术研究中心,广东广州510642

出　　处：《中国畜牧杂志》2025年第1期23-29,35,共8页Chinese Journal of Animal Science

基　　金：广东省重点领域研发计划(2022B0202090002)。

摘　　要：非编码RNA(Non-coding RNAs,ncRNAs)是由基因组转录形成的不编码蛋白质的一类RNA分子,根据其片段长度和结构可分为长链非编码RNA(lncRNA)、microRNA(miRNA)和环状RNA(circRNA)等,对基因的转录和翻译过程具有重要调控作用。随着高通量RNA测序(RNA-seq)等技术的发展,部分与胚胎附植和胎盘发育相关的非编码RNAs的生物学功能不断被揭示。本文综述了lncRNA、miRNA和circRNA等ncRNAs在猪胚胎附植和胎盘发育过程中的研究现状,以期为应用ncRNAs提高我国母猪的繁殖性能提供重要参考。Non-coding RNAs(ncRNAs)are a class of RNA molecules formed by genome transcription that do not encode proteins.According to their fragment length and structure,they can be divided into long non-coding RNA(lncRNA),microRNA(miRNA)and circRNA,etc.It plays an important role in regulating gene transcription and translation.With the development of high throughput RNA sequencing(RNA-SEQ)and other technologies,the biological functions of some noncoding RNAs related to embryo attachment and placental development have been continuously revealed.In this paper,the research status of ncRNAs such as lncRNA,miRNA and circRNA in pig embryo implantation and placental development was reviewed,in order to provide an important reference for the application of ncRNAs to improve the reproductive performance of sows in China.

关 键 词：非编码RNA 胎盘 胚胎附植 胎盘褶皱 胎盘发育 

分 类 号：S828.2[农业科学—畜牧学]