催乳素及其受体调控雄性生殖的作用机制  

Review on the Regulation of Male Reproduction by Prolactin and Its Receptors

作　　者：陈美静 尹雪姣 王泳 张英杰[1] CHEN Meijing;YIN Xuejiao;WANG Yong;ZHANG Yingjie(College of Animal Science and Technology,Hebei Agricultural University,Hebei Baoding 071000,China;College of Animal Science and Technology,Hebei Normal University of Science&Technology,Hebei Qinhuangdao China;Inner Mongolia Academy of Agricultural&Animal Husbandry Sciences,Inner Mongolia Hohhot 010031,China)

机构地区：[1]河北农业大学动物科技学院,河北保定071000 [2]河北科技师范学院动物科技学院,河北秦皇岛066000 [3]内蒙古自治区农牧业科学院,内蒙古呼和浩特010031

出　　处：《中国畜牧杂志》2025年第1期61-65,共5页Chinese Journal of Animal Science

基　　金：国家肉羊产业技术体系(CARS-38)。

摘　　要：催乳素,又名促乳素,是一种主要由垂体前叶泌乳素细胞合成分泌的多肽类激素,通过与催乳素受体结合发挥作用。催乳素参与动物生殖、泌乳、生长发育等多种行为的调控过程。目前,催乳素在雌性动物中的生殖生理作用已被广泛探讨,在雄性动物上的研究较少,但催乳素对精子生成及睾酮产生等发挥着重要作用。本文综述了催乳素的结构、分泌调节过程及对生殖的影响,并重点探讨了催乳素及其受体在雄性动物生殖中的调控机制等,以期为雄性生殖生理调控提供新思路。Prolactin is a peptide hormone synthesized and secreted mainly by prolactin cells in the anterior pituitary gland,and acts by binding to the prolactin-receptor.Prolactin is involved in the regulation of many behaviors in animals,including reproduction,lactation,growth and development.At present,the reproductive physiological role of prolactin has been widely explored in female animals and less studied in males,but prolactin plays an important role in spermatogenesis and testosterone production.Therefore,this paper reviews the structure,secretion regulation process and effects on reproduction of prolactin,and focuses on the regulatory mechanism of prolactin and its receptor in male animal reproduction,with a view to providing new ideas for the future physiological regulation of male reproduction.

关 键 词：催乳素 受体 睾丸功能 生殖调控 

分 类 号：S814[农业科学—畜牧学]