标准脉冲射频治疗少见部位血管球瘤的疗效与安全性  

Efficacy and safety of standard pulsed radiofrequency for treating rare-site glomus tumors

作　　者：王东 罗宇家 李云泽 盖祺 冯智英[1] WANG Dong;LUO Yujia;LI Yunze;GAI Qi;FENG Zhiying(Department of Pain,First Affiliated Hospital,School of Medicine,Zhejiang University,Hangzhou,Zhejiang 310003,China;Department of Pain,Yongkang Municipal First People’s Hospital,Yongkang,Zhejiang 321300,China)

机构地区：[1]浙江大学医学院附属第一医院疼痛科,杭州310003 [2]永康市第一人民医院疼痛科,浙江永康321300

出　　处：《重庆医学》2025年第1期76-79,85,共5页Chongqing Medical Journal

基　　金：浙江省科技厅领雁研发攻关计划(省重点研发)(2022C03081);中国红十字基金会医学赋能公益专项基金(CRCF-YXFN-202201070)。

摘　　要：目的探讨标准脉冲射频治疗少见部位血管球瘤的有效性和安全性。方法采用前瞻性自身前后对照研究方法,纳入2022年6月至2023年1月在永康市第一人民医院疼痛科确诊为血管球瘤的6例患者为研究对象,其中1例瘤体位于上臂三角肌外束,5例位于手指甲或足趾甲床下。所有受试者行超声引导下标准脉冲射频治疗,并进行了至少12个月的随访。观察患者术前及术后数字评定量表(NRS)评分变化,记录患者“典型三联征”改变、指甲生长基质愈合程度及疼痛复发情况。结果术后随访结果显示,所有患者NRS评分有明显下降。其中,4例患者采用标准射频治疗后疼痛未复发;1例患者术后6个月疼痛复发,最终通过外科手术切除瘤体。除1例患者出现短暂甲床下淤血外,未观察到其他明显不良事件。结论标准脉冲射频治疗对于少见部位血管球瘤引起的疼痛是一种安全且有效的治疗手段。Objective To explore the efficacy and safety of standard pulsed radiofrequency for treating rare-site glomus tumors.Methods A prospective self before-and-after control study was conducted and 6 patients diagnosed as glomus tumors in the pain department of Yongkang Municipal First People’s Hospital from June 2022 to January 2023 served as the study subjects.Among them,1 case was located in the outer beam of deltoid muscle in the upper arm,and 5 cases were located under the nail beds of the hands/feet.All subjects underwent the standard pulsed radiofrequency treatment under ultrasound guidance and were followed up for at least 12 months.The changes in the preoperative and postoperative Numerical Rating Scale(NRS)scores were observed,and the changes in the“typical triad”,healing degree of the nail growth matrix and recurrence of pain were recorded.Results The postoperative follow-up results showed that all patients had significant decreases in NRS scores,indicating that the pain degree obtained the effective control.Among them,4 patients did not experience the pain recurrence after adopting the standard pulsed radiofrequency;1 patient had pain recurrence in postoperative 6 months and the tumor body was ultimately removed by surgery.Apart from the patient 2 developing tra nsient subungual congestion,no significant adverse events were observed.Conclusion The standard pulsed radiofrequency treatment is a safe and effective therapeutic method for pain caused by rare-site glomus tumors.

关 键 词：甲外血管球瘤 甲下血管球瘤 标准脉冲射频治疗 慢性疼痛 安全性 

分 类 号：R614.4[医药卫生—麻醉学]