成人肝移植术后患者生存质量与焦虑抑郁状况的相关性及影响因素分析  

Correlation between survival quality and anxiety and depression status of adult patients after liver transplantation and influencing factors

作　　者：吴洪苇 潘耀振[2] 王兆北 陈玲 任婷婷 谭云 邓倩 WU Hongwei;PAN Yaozhen;WANG Zhaobei;CHEN Ling;REN Tingting;TAN Yun;DENG Qian(School of Nursing,Guizhou Medical University,Guiyang 550004,Guizhou,China;Deptment of Hepatobiliary Surgery,Guizhou Cancer Hospital,Guiyang 550008,Guizhou,China;Deptment of Hepatobiliary Surgery,the Affiliated Hospital of Guizhou Medical University,Guiyang 550004,Guizhou,China)

机构地区：[1]贵州医科大学护理学院,贵州贵阳550004 [2]贵州省肿瘤医院肝胆外科,550008 [3]贵州医科大学附属医院肝胆外科,贵州贵阳550004

出　　处：《贵州医科大学学报》2025年第1期109-114,共6页Journal of Guizhou Medical University

基　　金：贵州省卫生健康委科学技术基金项目(gzwkj2022-244)。

摘　　要：目的探讨成人肝移植术后门诊随访患者焦虑抑郁的发生情况、影响因素及与生存质量的关系。方法选择在贵州医科大学附属医院肝移植门诊接受随访的120例肝移植术后患者,采用自编的调查表收集患者的性别、年龄、收入及移植原因等一般资料,采用世界卫生组织生存质量测定简明量表(WHOQOL-BREF)评估患者的生存质量,采用Zung焦虑自评量表(SAS)和抑郁自评量表(SDS)评估患者的焦虑及抑郁状况,并分析生存质量与患者焦虑抑郁状况的相关性及风险因素。结果最终调查获得有效问卷114份,在114例肝移植患者中,WHOQOL-BREF的4个领域平均得分分别为社会关系领域(69.08±12.96)、心理领域(66.17±14.63)、环境领域(61.99±14.23)及生理领域(60.78±17.31);SAS平均得分为(54.55±11.25)、SDS平均得分为(56.82±12.03);将WHOQOL-BRE的4个领域得分与SAS、SDS得分做相关分析发现,WHOQOL-BREF的生理领域、心理领域和环境领域得分与SAS、SDS得分呈负相关(P<0.05);将患者一般资料和WHOQOL-BREF的生理领域、心理领域和环境领域得分纳入多元线性回归方程中进行分析,结果显示女性、低学历者和术后身体不适者及WHOQOL-BREF中生理领域、环境领域是SAS、SDS得分的主要影响因素(P<0.05)。结论肝移植术后患者的整体生存质量处于中等水平,WHOQOL-BREF得分越低,SAS、SDS得分越高,患者焦虑抑郁情况越严重,且女性患者、教育程度较低者以及术后持续经历身体不适的患者更易于出现焦虑和抑郁情绪,生理状况的波动及不良环境状况也是影响患者焦虑抑郁情绪的关键因素。Objective To explore the incidence of anxiety and depression of patients from outpatient follow-up after adult liver transplantation,influencing factors and their relationship with survival quality.Methods A total of 120 follow-up patients with liver transplant were selected from Outpatient Department of Liver Transplantation,the affiliated Hospital of Guizhou Medical University.A self-designed personal data questionnaire was used to collect general information such as gender,age,income and reason for transplantation.World Health Organization quality of life-brief scale(WHOQOL-BREF)was applied to assess survival quality of the patients.Zung's self-rating anxiety scale(SAS)and self-rating depression scale(SDS)were used to assess the anxiety and depression status of the patients.The patients were analyzed for the correlation between survival quality and the anxiety and depression status as well as risk factors.Results There were 114 valid questionnaires.Among 114 patients with liver transplantation,the mean scores of the four domains of WHOQOL-BREF were social QQL(69.08±12.96)points,psychological QQL(66.17±14.63)points,environmental QQL(61.99±14.23)points,and physiological QQL(60.78±17.31)points,respectively.SAS mean score was(54.55±11.25)points,and SDS mean score was(56.82±12.03)points.Association analysis of the 4 domain scores of WHOQOL-BREF with SAS score and SDS score revealed that the scores of the physiological domain,psychological domain and environmental domain of WHOQOL-BRE were negatively correlated with SAS score and SDS score(P<0.05).Basic information of the patients and the scores of physiological domains,psychological domains and environmental domains of WHOQOL-BREF scale were included in the multiple linear regression equations and analyzed,and the results showed that female patients,low-educated patients and those who were physically unwell in the postoperative period,the scores of physiological domains and environmental domains of WHOQOL-BREF scale were the factors that influenced the scores

关 键 词：肝移植 生存质量 焦虑 抑郁 

分 类 号：R473.56[医药卫生—护理学]