黄金火龙灸治疗寒饮伏肺证慢性阻塞性肺疾病急性加重期患者的疗效  

Efficacy of Golden Fire Dragon Moxibustion in the Treatment of Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease and Cold Drink Latent Lung Syndrome

作　　者：金华伟 刘新宇 叶焰 JIN Huawei;LIU Xinyu;YE Yan(Department of Respiratory,the Affiliated Traditional Chinese Medicine Hospital,Guangzhou Medical University,Guangzhou 510130,China)

机构地区：[1]广州医科大学附属中医医院呼吸科,广东省广州市510130

出　　处：《实用心脑肺血管病杂志》2025年第3期93-98,共6页Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease

基　　金：广州市中医药和中西医结合科技项目(20242A010004)。

摘　　要：目的探讨黄金火龙灸治疗寒饮伏肺证慢性阻塞性肺疾病急性加重期(AECOPD)患者的疗效。方法选取2021年6月—2023年6月广州医科大学附属中医医院呼吸科收治的寒饮伏肺证AECOPD患者65例为研究对象,采用随机数字表法将其分为常规治疗组(n=32)和黄金火龙灸组(n=33),试验过程中常规治疗组脱落及剔除2例患者,黄金火龙灸组脱落及剔除3例患者,剩余60例患者,其中常规治疗组30例、黄金火龙灸组30例。常规治疗组患者接受常规西医治疗,黄金火龙灸组患者在常规治疗组的基础上接受黄金火龙灸疗法,两组疗程均为10 d。比较两组临床疗效,治疗前后肺功能指标[第1秒用力呼气容积(FEV_(1))、用力肺活量(FVC)、FEV_(1)/FVC]、免疫功能指++++标(CD_(4)^(+)T淋巴细胞、CD_(8)^(+)T淋巴细胞百分数及CD_(4)^(+)T淋巴细胞/CD_(8)^(+)T淋巴细胞比值)、炎症指标[白介素6(IL-6)、白介素17(IL-17)、肿瘤坏死因子α(TNF-α)]、气道重塑指标[管壁厚度(WT)、气道壁面积占气道总横截面积百分比(WA%)、管壁厚度与外径比值(T/D)]、6分钟步行距离(6MWD)、慢性阻塞性肺疾病评估测试(CAT)评分。结果黄金火龙灸组总有效率高于常规治疗组(P<0.05)。治疗后,黄金火龙灸组FEV_(1)、FVC、+++FEV_(1)/FVC高于常规治疗组(P<0.05)。治疗后,黄金火龙灸组CD_(4)^(+)T淋巴细胞百分数、CD_(4)^(+)T淋巴细胞/CD_(8)^(+)T淋+巴细胞比值高于常规治疗组,CD_(8)^(+)T淋巴细胞百分数低于常规治疗组(P<0.05)。治疗后,黄金火龙灸组IL-6、IL-17、TNF-α低于常规治疗组(P<0.05)。治疗后,黄金火龙灸组WT小于常规治疗组,WA%、T/D低于常规治疗组(P<0.05)。治疗后,黄金火龙灸组6MWD长于常规治疗组,CAT评分低于常规治疗组(P<0.05)。结论黄金火龙灸可提高寒饮伏肺证AECOPD患者的临床疗效,改善肺功能、免疫功能,减轻炎症反应,抑制气道重塑,并提高患者的运动耐力及生活质量。Objective To investigate the efficacy of golden fire dragon moxibustion in the treatment of patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD)and cold drink latent lung syndrome.Methods A total of 65 patients with AECOPD and cold drink latent lung syndrome admitted to Department of Respiratory of the Affiliated Traditional Chinese Medicine Hospital,Guangzhou Medical University from June 2021 to June 2023 were selected as the study subjects.The patients were divided into the conventional treatment group(n=32)and the golden fire dragon moxibustion group(n=33)by random number table method.During the experiment,2 cases were removed from the conventional treatment group,3 cases were removed from the golden fire dragon moxibustion group,and 60 patients remained,including 30 cases in the conventional treatment group and 30 cases in the golden fire dragon moxibustion group.The patients in the conventional treatment group received conventional western medicine treatment;the patients in the golden fire dragon moxibustion group received golden fire dragon moxibustion therapy on the basis of the conventional treatment group,both groups were treated for 10 days.The clinical effect,pulmonary function indicators[forced expiratory volume in one second(FEV_(1)),forced vital capacity(FVC),FEV_(1)/FVC],immune function++++indicators(percentage of CD_(4)^(+)T lymphocytes and CD_(8)^(+)T lymphocytes,CD_(4)^(+)T lymphocytes/CD_(8)^(+)T lymphocytes),inflammatory indicators[interleukine-6(IL-6),interleukine-17(IL-17),tumor necrosis factor-α(TNF-α)],airway remodeling indicators[wall thickness(WT),percentage of airway wall area to total airway cross sectional area(WA%),wall thickness/outer diameter(T/D)],6-minute walking distance(6MWD)and Chronic Obstructive Pulmonary Disease Assessment Test(CAT)score before and after treatment were compared between the two groups.Results After treatment,the total effective rate of golden fire dragon moxibustion group was higher than that of conventional treatment group(P<0

关 键 词：肺疾病 慢性阻塞性 寒饮伏肺证 督灸疗法 治疗结果 

分 类 号：R563.9[医药卫生—呼吸系统]