强直性脊柱炎继发骨质疏松症诊断与治疗临床实践指南  

Clinical practice guidelines for the diagnosis and treatment of osteoporosis secondary to ankylosing spondylitis

作　　者：浙江省医师协会骨质疏松与骨矿盐疾病专业委员会 中国老年学和老年医学学会骨质疏松和骨内科分会 李涯松[2] Zhejiang Medical Association Osteoporosis and Bone Mineral Disease Committee;Osteoporosis Society of China Association of Gerontology and Geriatrics

机构地区：[1]不详 [2]浙江省人民医院

出　　处：《中华全科医学》2025年第1期5-16,共12页Chinese Journal of General Practice

基　　金：国家中医药管理局-浙江省中医药管理局共建重点项目(GZY-ZJ-KJ-23047)。

摘　　要：强直性脊柱炎(AS)是一种以脊柱、骶髂关节等中轴关节受累为主的慢性炎症性疾病,AS可以并发多系统病变,其中继发性骨质疏松常见,目前国内外尚无相关诊治共识或指南。本指南由浙江省医师协会骨质疏松与骨矿盐疾病专业委员会、兰州大学循证医学中心、中国老年学和老年医学学会骨质疏松和骨内科分会联合牵头发起,采用英国牛津分级体系和国际实践指南报告标准(RIGHT),就我国一线风湿免疫科、骨科医师关注的11个临床问题,给出了较为详细的循证推荐,旨在提高AS继发骨质疏松诊疗的科学性,提高以患者为中心的医疗服务质量。Ankylosing spondylitis(AS)is a chronic inflammatory disease primarily affecting the axial skeleton,including the spine and sacroiliac joints.AS can lead to multi-system complications,with secondary osteoporosis being common.Currently,there are no relevant consensus or guidelines on diagnosis and treatment domestically or internationally.This guideline was jointly initiated by the Zhejiang Medical Association Osteoporosis and Bone Mineral Disease Committee,the Evidence-Based Medicine Center of Lanzhou University,and the Osteoporosis Society of China Association of Gerontology and Geriatrics.It follows the Oxford grading system and the Reporting Items for Practice Guidelines in Healthcare(RIGHT),providing detailed,evidence-based recommendations on eleven clinical questions concerned by frontline rheumatologists and orthopedists in our country.The guidelines aim to strengthen the scientific basis for diagnosing and treating osteoporosis secondary to AS while improving the quality of patient-centered healthcare.

关 键 词：强直性脊柱炎 骨质疏松 指南 证据质量与推荐强度分级 

分 类 号：R593.23[医药卫生—内科学] R681[医药卫生—临床医学]