单一使用盐酸达泊西汀与联合“动停”行为学训练在治疗原发性早泄中的临床研究  

Clinical study of single use of dapoxetine hydrochloride and combined“Start-Stop Training”in the treatment of lifelong premature ejaculation

作　　者：高晶晶[1] 张子房 杜俊华[1] 高攀[1] 彭党委 张耀[1] 张贤生[1] Gao Jingjing;Zhang Zifang;Du Junhua;Gao Pan;Peng Dangwei;Zhang Yao;Zhang Xiansheng(The First Affiliated Hospital of Anhui Medical University,Hefei 230022,Anhui,China)

机构地区：[1]安徽医科大学第一附属医院,安徽合肥230022

出　　处：《中国男科学杂志》2024年第6期48-52,共5页Chinese Journal of Andrology

基　　金：国家自然科学基金(82371635)。

摘　　要：目的探讨单一使用盐酸达泊西汀与联合“动停”行为学训练(SST)在治疗原发性早泄(LPE)中的临床效果。方法将2017年9月至2021年12月因LPE就诊于我院男科门诊的患者随机分为单一盐酸达泊西汀治疗组和联合SST治疗组(每组30人)。治疗4周和8周后对患者进行疗效评估,包括射精潜伏期(IELT)和中国早泄患者性功能评价表(CIPE)的变化。结果联合治疗组和单一盐酸达泊西汀治疗组患者平均年龄分别为(32.47±4.87)岁和(32.87±6.36)岁(P>0.05)。两组IELT和CIPE得分较治疗前均有一定的改善。联合治疗组IELT的改善和CIPE得分的变化显著优于盐酸达泊西汀治疗组(P<0.05),主要在IELT的提升比例和CIPE得分的上升幅度。结论联合治疗组在综合治疗LPE方面显著优于单一盐酸达泊西汀治疗组。Objective To investigate the clinical effect of single dapoxetine hydrochloride and combined motor-stop behavioral training(SST)in the treatment of primary premature ejaculation(LPE).Methods Patients presenting to our andrology clinic for LPE from September 2017 to December 2021 were randomly divided into single darpoxetine hydrochloride and combined SST treatment group(30 patients in each group).Patients were evaluated for efficacy after 4 weeks and 8 weeks of treatment,including changes in Intra-vaginal ejaculation latency time(IELT)and Chinese index of sexual function for premature ejaculation(CIPE).Results The mean age of patients in the combination group and single dapoxetine hydrochloride group was(32.47±4.87)years and(32.87±6.36)years(P>0.05),respectively.Both IELT and CIPE scores improved somewhat compared to before treatment.The improvement in IELT and the change in CIPE score in the combination treatment group were significantly better than those in the dapoxetine hydrochloride treatment group(P<0.05),mainly in the proportion of IELT improvement and the increase in CIPE score.Conclusion The combination group was significantly better than the single dapoxepine hydrochloride group in treating LPE.

关 键 词：达泊西汀 “动停”训练 早泄 

分 类 号：R698.3[医药卫生—泌尿科学] R454.9[医药卫生—外科学]