多参数MRI鉴别黄色肉芽肿性胆囊炎与厚壁型胆囊癌的诊断效能研究  

Diagnostic Efficacy of Multi-parameter MRI in Differentiating Xanthogranulomatous Cholecystitis from Thick-walled Gallbladder Cancer

作　　者：王晓燕 胡鹏[2] Wang Xiaoyan;Hu Peng(Department of Radiology,Xiaoshan Hospital Affiliated to Hangzhou Normal University,Hangzhou,Zhejiang 311202;Department of Radiology,Sir Run Run Shaw Hospital Affiliated to School of Medicine of Zhejiang University,Hangzhou,Zhejiang 310016)

机构地区：[1]杭州师范大学附属萧山医院放射科,浙江杭州311202 [2]浙江大学医学院附属邵逸夫医院放射科,浙江杭州310016

出　　处：《现代医用影像学》2024年第11期2058-2063,共6页Modern Medical Imageology

摘　　要：目的:探讨多参数MRI在鉴别黄色肉芽肿性胆囊炎(XGC)与厚壁型胆囊癌(GBC)中的诊断效能。方法:回顾性收集并分析经病理证实的XGC和GBC患者的临床及MRI资料。结果:共235例(XGC 117例,GBC 118例)患者纳入本研究。在XGC患者中,胆囊黏膜线连续、壁内结节及其在反相位信号强度降低更为常见(P<0.001)。常规MRI联合化学位移成像后,两位放射医师的诊断准确性、敏感性及特异性均有明显提高,且常规MRI联合化学位移成像鉴别诊断XGC与厚壁型GBC的受试者工作特征曲线下面积(AUC=0.878)大于常规MRI(AUC=0.738)。结论:多参数MRI可显著提高临床医师鉴别XGC和厚壁型GBC的诊断效能,这有助于提高临床医师对这两种胆囊疾病的鉴别诊断水平。Purpose:To explore the diagnostic efficacy of multi-parameter MRI in differentiating xanthogranulomatous cholecystitis(XGC)from thick-walled gallbladder carcinoma(GBC).Methods:We retrospectively collected and analyzed clinical and MRI data of patients with XGC and thick-walled GBC who were pathologically confirmed.Results:A total of 235 patients were included(XGCs 117,GBCs 118).In patients with XGC,continuous mucosal lines,intramural nodules and signal intensity decay were more common on out phase images(P<0.001).After conventional MRI combined with chemical shift images,the diagnostic accuracy,sensitivity,and specificity of the two radiologists have significantly improved,the area under receiver operating characteristic curve(AUC)of conventional MRI combined with chemical shift imaging(AUC=0.878)for differential diagnosis of XGC and thick-walled GBC was greater than that of conventional MRI(AUC=0.738).Moreover,the consistency between the radiologists was excellent.Conclusion:Multi-parametric MRI can improve the diagnostic efficacy of clinicians in distinguishing between XGC and thick-walled GBC,which is helpful to improve the clinicians level of differential diagnosis of the two diseases.

关 键 词：黄色肉芽肿性胆囊炎 厚壁型胆囊癌 MRI 

分 类 号：R65[医药卫生—外科学]