微通道法制备N-丁基-4-硝基邻苯二甲酰亚胺  

Preparation of N-Butyl-4-Nitrophthalimide with Microchannel Reactor

作　　者：韩东 丁兴成 王迪 章文刚 HAN Dong;DING Xingcheng;WANG Di;ZHANG Wengang(Zhejiang Runtu Co.,Ltd.,Shaoxing 312300,Zhejiang China)

机构地区：[1]浙江闰土股份有限公司,绍兴312369

出　　处：《染料与染色》2024年第6期35-38,共4页Dyestuffs and Coloration

摘　　要：本文以微通道装置作为反应器,对微通道制备N-丁基-4-硝基邻苯二甲酰亚胺的各个因素进行了探究,得到相对优化的反应条件:浓硫酸∶N-丁基邻苯二甲酰亚胺质量比为2∶1;浓硝酸∶N-丁基邻苯二甲酰亚胺硝化摩尔比为1.15∶1;反应温度51~55℃;体系压力0.5 MPa;停留时间4.0~4.5 min。该条件下,N-丁基-4-硝基邻苯二甲酰亚胺的中控含量在91%以上。N-Butyl-4-nitrophthalimide was prepared with microchannel reactor and effect factors of the reaction were studied.The optimum reaction conditions were obtained:the mass ratio of sulfuric acid:N-butylphthalimide was 2∶1,the molar ratio of nitric acid:N-butylphthalimide was 1.15∶1,the reaction temperature was 51~55℃,the reaction pressure was 0.5 MPa,and the reaction residence time was 4.5~5.5 min.In the condition,the purity of N-butyl-4-nitrophthalimide was over 91%.

关 键 词：微通道反应器 N-丁基-4-硝基邻苯二甲酰亚胺 硝化反应 

分 类 号：O62[理学—有机化学]