不同浓度轻比重罗哌卡因在髋关节置换术中的应用效果  

Application Effect of Different Concentrations of Hypobaric Ropivacaine in Hip Replacement

作　　者：黄书玲 陈丽 孙磊 HUANG Shuling;CHEN Li;SUN Lei(Department of Anesthesiology,Jian'ou Municipal Hospital,Nanping 353100,Fujian,China)

机构地区：[1]建瓯市立医院麻醉科,福建南平353100

出　　处：《中国药物滥用防治杂志》2024年第12期2188-2189,2192,共3页Chinese Journal of Drug Abuse Prevention and Treatment

基　　金：福建省卫生计生青年科研课题(编号:2023-6-22)。

摘　　要：目的:探讨不同浓度轻比重罗哌卡因在髋关节置换术中的应用效果。方法:于2022年9月—2023年12月,行便利抽样法择取行髋关节置换术患者90例进行研究,随机分组A组(n=30,轻比重0.15%)、B组(n=30,轻比重0.25%)、C组(n=30,轻比重0.50%),均予以腰硬联合麻醉(单侧),比较三组麻醉镇痛效果、血流动力学及安全性。结果:相较于A组,B组及C组感觉及运动起效时间均更短,感觉及运动恢复时间均更长,补救镇痛次数更少(P<0.05);相较于B组,C组感觉及运动起效时间均更短,感觉及运动恢复时间均更长(P<0.05),但补救镇痛次数无明显差异(P>0.05);相较于T0时点,三组T_(1)、T_(2)时点MAP、HR均更低(P<0.05),且C组T_(1)、T_(2)时点MAP、HR均低于A组、B组(P<0.05);C组不良反应发生率高于A、B组(P<0.05),但A、B组无明显差异(P>0.05)。结论:轻比重0.25%罗哌卡因单侧腰硬联合麻醉用于髋关节置换术麻醉镇痛效果良好,血流动力学干扰小,且具有较高安全性。Objective:To investigate the application effect of different concentrations of hypobaric ropivacaine in hip replacement.Methods:From September 2022 to December 2023,90 patients undergoing hip replacement were selected by convenient sampling method.They were randomly divided into group A(n=30,light specific gravity 0.15%),group B(n=30,light ratio weight 0.25%),group C(n=30,light ratio weight 0.50%),all of which were given combined spinal-epidural anesthesia(unilateral).The analgesic effect,hemodynamics and safety of the three groups were compared.Results:Compared with group A,the onset time of sensation and movement in group B and group C was shorter,the recovery time of sensation and movement was longer,and the number of remedial analgesia was less(P<0.05).Compared with group B,the onset time of sensation and movement in group C was shorter,and the recovery time of sensation and movement was longer(P<0.05),but there was no significant difference in the number of remedial analgesia(P>0.05).Compared with TO,the MAP and HR of the three groups at T_(1) and T_(2) were lower(P<0.05),and the MAP and HR of group C at T_(1) and T_(2) were lower than those of group A and group B(P<0.05).The incidence of adverse reactions in group C was higher than that in groups A and B(P<0.05),but there was no significant difference between groups A and B(P>0.05).Conclusion:Light specific gravity 0.25%ropivacaine unilateral combined spinal-epidural anesthesia for hip replacement anesthesia analgesia effect is good,hemodynamic interference is small,and has high safety.

关 键 词：罗哌卡因 髋关节置换术 腰硬联合麻醉 浓度 

分 类 号：R61[医药卫生—外科学]