药师抗菌药物管理实践对住院患者抗菌药物使用情况的影响  

Effect of Pharmacist's Antibacterial Drug Management Practice on the Use of Antibacterial Drugs in Hospitalized Patients

作　　者：丁广胜 宋璟瑞 花威 代坤 王丽 DING Guangsheng;SONG Jingrui;HUA Wei;DAI Kun;WANG Li(Clinical Pharmacy Department of Xinyang People's Hospital,Xinyang 464000,Henan,China)

机构地区：[1]信阳市人民医院临床药学室,河南信阳464000

出　　处：《中国药物滥用防治杂志》2024年第12期2206-2207,共2页Chinese Journal of Drug Abuse Prevention and Treatment

基　　金：2023年度信阳市重点研发与推广专项项目(编号:20230050)。

摘　　要：目的:分析药师主导的抗菌药物管理对住院患者抗菌药物使用的效果。方法:选取我院2022年5月—2023年8月期间收治的住院患者410例作为研究对象,其中2022年5—12月期间收治的住院患者205例作为常规组,均行常规抗菌药物管理;而2023年1—8月期间收治的住院患者205例作为观察组,实施药师主导的抗菌药物管理。比较两组治疗效果、不合理应用状况及不良反应发生率。结果:观察组总有效率为97.07%,高于常规组的77.07%(P<0.05);观察组用量/用药不当率、药物选择不当率、联合用药不当率、用药疗程过长率、用药时机不恰当率、无指征用药占比低于常规组(P<0.05);观察组不良反应发生率为3.90%,低于常规组的26.34%(P<0.05)。结论:药师主导的抗菌药物管理可提高住院患者抗菌药物的治疗效果,降低不合理应用状况,并减少不良反应的发生。Objective:To analyze the effect of pharmacist-led antibacterial drug management on the use of antibacterial drugs in hospitalized patients.Methods:A total of 410 inpatients admitted to our hospital from May 2022 to August 2023 were selected as the research objects,and 205 inpatients admitted to our hospital from May 2022 to December 2022 were selected as the routine group.All patients underwent routine antibacterial drug management;from January to August 2023,205 inpatients were treated as the observation group,and the pharmacist-led antimicrobial drug management was implemented.The therapeutic effect,unreasonable application status and incidence of adverse reactions were compared between the two groups.Results:The total effective rate of the observation group was 97.07%,which was higher than 77.07%of the conventional group(P<0.05).The dosage/improper medication rate,improper drug selection rate,improper combination medication rate,excessive medication course rate,improper medication timing rate,and proportion of non-indication medication in the observation group were lower than those in the conventional group(P<0.05).The incidence of adverse reactions in the observation group was 3.90%,which was lower than 26.34%in the conventional group(P<0.05).Conclusion:Pharmacist-led antimicrobial drug management can improve the therapeutic effect of antimicrobial drugs in hospitalized patients,reduce the unreasonable application and reduce the incidence of adverse reactions.

关 键 词：药师 抗菌药物 住院患者 不良反应 

分 类 号：R47[医药卫生—护理学]