岭南火针治疗斑块型银屑病的临床疗效观察  

Clinical Observation on the Therapeutic Efficacy of Lingnan Fire Needling for Plaque Psoriasis

作　　者：李晶晶 陈锐明 石国傲 吴婷 徐海燕 陈世云 张现豪 陈文 黄前鹏 郭国建 秦烨 周鹏 LI Jingjing;CHEN Ruiming;SHI Guo'ao;WU Ting;XU Haiyan;CHEN Shiyun;ZHANG Xianhao;CHEN Wen;HUANG Qianpeng;GUO Guojian;QIN Ye;ZHOU Peng(Bao'an Hospital of Chinese Medicine Affiliated to Guangzhou University of Chinese Medicine/The Seventh Clinical Medical School of Guangzhou University of Chinese Medicine,Shenzhen 518133 Guangdong,China)

机构地区：[1]广州中医药大学附属宝安中医院/广州中医药大学第七临床医学院,广东深圳518133

出　　处：《广州中医药大学学报》2025年第2期382-389,共8页Journal of Guangzhou University of Traditional Chinese Medicine

基　　金：国家自然科学基金青年基金项目(编号:82405559);深圳市科技创新委员会基础研究专项(编号:JCYJ20230807115501002);广东省中医药局科研项目(编号:20211340)。

摘　　要：【目的】观察岭南火针治疗斑块型银屑病的临床疗效。【方法】选取2021年8月至2023年1月期间广州中医药大学附属宝安中医院收治的斑块型银屑病患者60例,按随机数字表将患者随机分为观察组和对照组,每组各30例。观察组给予岭南火针治疗,对照组给予卡泊三醇软膏外用。连续治疗8周。治疗8周后,评价2组临床疗效,观察2组患者治疗前及治疗2、4、6、8周后皮损面积和严重程度指数(PASI)评分与皮肤病生活质量指数量表(DLQI)评分的变化情况,以及皮肤镜下血管球直径的情况。比较2组患者治疗前及治疗2、4、6、8周后广泛性焦虑障碍量表(GAD-7)评分的变化情况。【结果】(1)治疗2、4、6、8周后,2组患者的PASI评分、DLQI评分与GAD-7评分均明显改善(P<0.05),且观察组在改善PASI评分、DLQI评分与GAD-7评分方面均明显优于对照组,差异有统计学意义(P<0.05)。(2)观察组愈显率为86.67%(26/30);对照组为66.67%(20/30)。观察组疗效优于对照组,差异有统计学意义(P<0.05)。(3)治疗2、4、6、8周后,2组患者的皮肤镜下血管球平均直径明显改善(P<0.05),且观察组在改善血管球平均直径方面明显优于对照组,差异有统计学意义(P<0.05)。【结论】岭南火针治疗斑块型银屑病,能够有效改善患者的临床症状,缓解患者因皮损及瘙痒导致的焦虑症状,从而提高患者的生活质量,疗效显著。Objective To observe the clinical efficacy of Lingnan fire needling in the treatment of plaque psoriasis.Methods A total of 60 cases of patients with plaque psoriasis admitted to Bao'an Hospital of Chinese Medicine Affiliated to Guangzhou University of Chinese Medicine from August 2021 to January 2023 were selected,and the patients were randomly divided into the observation group and the control group according to the random number table method,with 30 cases in each group.The observation group was given Lingnan fire needling for treatment,and the control group was given topical application of Calcipotriol Ointment.The course of treatment covered eight weeks continuously.After eight weeks of treatment,the clinical efficacy of the two groups was evaluated,and the changes of Psoriasis Area and Severity Index(PASI)scores and Dermatology Life Quality Index(DLQI)scores,as well as the diameter of glomus under dermoscopy of the patients in the two groups were observed before the treatment and after 2,4,6,and 8 weeks of treatment.Changes in Generalized Anxiety Disorder Scale(GAD-7)scores before treatment and after 2,4,6,and 8 weeks of treatment were compared between the two groups.Results(1)After 2,4,6 and 8 weeks of treatment,the scores of PASI,DLQI and GAD-7 of patients in the two groups were improved significantly(P<0.05),and the improvement in the observation group was significantly superior to that in the control group,the difference being statistically significant(P<0.05).(2)The cured and markedly rate of the observation group was 86.67%(26/30);and that of the control group was 66.67%(20/30).The efficacy of the observation group was superior to that of the control group,the difference being statistically significant(P<0.05).(3)After 2,4,6,and 8 weeks of treatment,the diameter of glomus under dermoscopy of the patients in the two groups were improved significantly(P<0.05),and the improvement in the observation group was significantly superior to that in the control group,the difference being statistically significant

关 键 词：岭南火针 银屑病 斑块型 皮肤镜 皮损 瘙痒 焦虑 临床疗效 

分 类 号：R246.9[医药卫生—针灸推拿学]