炙甘草汤加减联合针刺治疗气阴两虚型室性心律失常的临床观察  

Clinical Observation on Modified Zhi Gancao Decoction Combined with Acupuncture in the Treatment of Ventricular Arrhythmia with Qi and Yin Deficiency Type

作　　者：曹丽娟[1,2] 李滕 宁微 何涛 杨威 CAO Lijuan;LI Teng;NING Wei;HE Tao;YANG Wei(Heilongjiang University of Chinese Medicine,Harbin 150036 Heilongjiang,China;Hospital of Traditional Chinese Medicine of Qiqihar,Qiqihar 161005 Heilongjiang,China)

机构地区：[1]黑龙江中医药大学,黑龙江哈尔滨150036 [2]齐齐哈尔市中医医院,黑龙江齐齐哈尔161005

出　　处：《广州中医药大学学报》2025年第1期57-63,共7页Journal of Guangzhou University of Traditional Chinese Medicine

基　　金：国家自然科学基金青年科学基金资助项目(编号:82104962);黑龙江省青年人才托举工程项目资助项目(编号:2022-QNRC1-28);齐齐哈尔市科技攻关资助项目(编号:CSFGG-2023161,CSFGG-2023181)。

摘　　要：【目的】观察炙甘草汤加减联合针刺治疗气阴两虚型室性心律失常的临床疗效。【方法】选取2023年1月至2024年1月期间于齐齐哈尔市中医医院病房及门诊收治的气阴两虚型室性心律失常患者60例,按随机数字表法将患者随机分为观察组和对照组,每组各30例。对照组给予盐酸美西律片治疗,观察组在对照组治疗的基础上,给予炙甘草汤加减联合针刺治疗,连续治疗2周。治疗2周后,评价2组中医证候疗效及Lown分级疗效,观察2组患者治疗前后室性早搏次数及占总心搏比的变化情况,以及中医证候积分的情况。比较2组患者治疗前后QT间期及Tp-ec间期的变化情况。【结果】(1)治疗后,2组患者的室性早搏次数及占总心搏比均明显改善(P <0.05),且观察组在改善室性早搏次数及占总心搏比方面明显优于对照组,差异有统计学意义(P <0.05)。(2)治疗后,2组患者的中医证候积分明显改善(P <0.05),且观察组在改善中医证候积分方面明显优于对照组,差异有统计学意义(P <0.05)。(3)观察组中医证候疗效总有效率为90.00%(27/30),对照组为60.00%(18/30)。观察组疗效优于对照组,差异有统计学意义(P <0.05)。(4)观察组Lown分级疗效总有效率为93.33%(28/30),对照组为76.67%(23/30)。观察组疗效优于对照组,差异有统计学意义(P <0.05)。(5)治疗后,2组患者的QT间期与Tp-ec间期明显改善(P <0.05),且观察组在改善QT间期与Tp-ec间期方面明显优于对照组,差异有统计学意义(P <0.05)。【结论】炙甘草汤加减联合针刺治疗气阴两虚型室性心律失常,能明显改善患者的临床症状,疗效显著。Objective To observe the clinical efficacy of modified Zhi Gancao Decoction combined with acupuncture in the treatment of ventricular arrhythmia with qi and yin deficiency type.Methods Sixty patients with ventricular arrhythmia of qi and yin deficiency type admitted to the wards and outpatient clinics of Hospital of Traditional Chinese Medicine of Qiqihar between January 2023 and January 2024 were selected,and the patients were randomly divided into the observation group and the control group according to the random number table method,with 30 patients in each group.The control group was treated with Mexiletine Hydrochloride Tablets,and the observation group was treated with modified Zhi Gancao Decoction combined with acupuncture on the basis of the treatment of the control group,the course of treatment covered two consecutive weeks.After two weeks of treatment,the efficacy of traditional Chinese medicine(TCM)syndrome and Lown grading were evaluated between the two groups,the changes of the number of ventricular premature beats,the total beat ratio,and TCM syndrome scores before and after treatment in the two groups were observed.The changes of QT interval and Tp-ec interval before and after treatment were compared between the two groups.Results(1)After treatment,the number of premature ventricular beats and the total beat ratio of the two groups were improved significantly(P<0.05),and the improvement in the observation group was significantly superior to that in the control group,the difference being statistically significant(P<0.05).(2)After treatment,the TCM syndrome scores of patients in the two groups were improved significantly(P<0.05),and the improvement in the observation group was significantly superior to that in the control group,the difference being statistically significant(P<0.05).(3)The total effective rate of TCM syndrome in the observation group was 90.00%(27/30),and 60.00%(18/30)in the control group.The efficacy of the observation group was superior to that of the control group,the difference be

关 键 词：炙甘草汤 针刺 气阴两虚 室性心律失常 临床观察 

分 类 号：R246.9[医药卫生—针灸推拿学]