镍对血糖代谢异常影响的研究进展  

Research progress on the effect of nickel on abnormal blood glucose metabolism

作　　者：蒋青桃 周静 王芹 刘炘 JIANG Qingtao;ZHOU Jing;WANG Qin;LIU Xin(School of Clinical Medicine,Jiangsu Health Vocational College,Nanjing,Jiangsu 211800,China;Institute of Occupational Disease Prevention and Control,Jiangsu Provincial Center for Disease Control and Prevention(Jiangsu Provincial Academy of Preventive Medicine),Nanjing,Jiangsu210028,China)

机构地区：[1]江苏卫生健康职业学院临床学院,江苏南京211800 [2]江苏省疾病预防控制中心(江苏省公共卫生研究院)职业病防治所,江苏南京210028

出　　处：《职业与健康》2024年第23期3297-3301,共5页Occupation and Health

基　　金：江苏省卫生健康委医学科研面上项目(M2022036);江苏省卫生健康职业学院重点项目(校20220010);江苏省高等学校基础科学(自然科学)面上项目(21KJD320006)。

摘　　要：镍是生产生活环境中的常见元素,过量的镍暴露会引起人群一系列健康危害。随着人们生活改善,糖尿病在全球范围内流行形势日趋严峻,已成为重要公共卫生问题。研究发现,镍暴露与血糖代谢异常间可能存在相关性,但这种相关性尚存在一定争议。本文通过收集分析镍与血糖代谢异常影响的研究成果,对镍致血糖代谢异常的研究进展进行综述,为探索重金属的内分泌代谢毒性及其相关机制提供参考。Nickel is a common element in production and living environment,and excessive exposure to nickel can cause a series of health hazards to the population.With the improvement of people's lives,the prevalence of diabetes in the world is becoming increasingly serious,and has become an important public health problem.The study found that there may be a correlation between nickel exposure and abnormal blood glucose metabolism,but this correlation is still controversial.This article summarizes the research progress on nickel induced abnormal blood glucose metabolism by collecting and analyzing the research results on the effects of nickel on abnormal blood glucose metabolism,providing reference for exploring the endocrine metabolic toxicity of heavy metals.

关 键 词：镍 血糖代谢异常 毒性 流行病学 机制 

分 类 号：R181.3[医药卫生—流行病学]