宏基因组测序技术在重症感染疾病中的应用进展  

Progress in Application of Metagenomic Sequencing Technology in Severe Infectious Diseases

作　　者：徐柳炎 钟娟[1] Xu Liuyan;Zhong Juan(The First People's Hospital of Nanning,Nanning 530022,Guangxi Zhuang Autonomous Region,China)

机构地区：[1]南宁市第一人民医院,广西壮族自治区南宁530022

出　　处：《中国社区医师》2025年第2期6-8,共3页Chinese Community Doctors

基　　金：广西南宁市科技局重大科技专项(编号:20203052)。

摘　　要：宏基因组测序(mNGS)技术可通过检测患者的核酸样本,快速、客观地识别多种病原微生物,协助临床精准定位靶向病原体,在重症感染性疾病患者病原微生物检测中具有较高的应用价值。该文对近年来mNGS技术在重症感染性疾病中的相关研究进行综述,特别是呼吸系统、中枢神经系统、血流感染及消化系统感染等领域的应用研究,以期为临床重症感染性疾病的诊治提供参考。Metagenomicnext-generationsequencing(mNGS)technology can detect nucleic acid samples from patients,quickly and objectively identify various pathogenic microorganisms,and assist clinical accurate positioning of targeted pathogens.It has high application value in the detection of pathogenic microorganisms in patients with severe infectious diseases.This paper reviews the researches on the mNGStechnologyin severe infectious diseasesin recent years,especially in the fields of respiratory system,central nervous system,blood stream infection and digestive system infection,so as to provide reference for clinical diagnosis and treatment of severe infectious diseases.

关 键 词：宏基因组测序技术 重症感染 研究进展 

分 类 号：R44[医药卫生—诊断学]