Dietary supplementation of valine,isoleucine,and tryptophan may overcome the negative effects of excess leucine in diets for weanling pigs containing corn fermented protein  

作　　者：Andrea P.Mallea Charmaine D.Espinosa Su A Lee Minoy A.Cristobal Leidy J.Torrez‑Mendoza Hans H.Stein 

机构地区：[1]Division of Nutritional Sciences,University of Illinois,Urbana,IL 61801,USA [2]Department of Animal Sciences,University of Illinois,Urbana,IL 61801,USA [3]Present Address:EnviroFlight,Raleigh,NC,USA.

出　　处：《Journal of Animal Science and Biotechnology》2025年第1期267-281,共15页畜牧与生物技术杂志(英文版)

基　　金：Financial support for this research from Minnesota Corn Growers Association(Burnsville,MN,USA);Green Plains Energy(Omaha,NE,USA)is greatly appreciated.

摘　　要：Background Diets with high inclusion of corn co-products such as corn fermented protein(CFP)may contain excess Leu,which has a negative impact on feed intake and growth performance of pigs due to increased catabolism of Val and Ile and reduced availability of Trp in the brain for serotonin synthesis.However,we hypothesized that the negative effect of using CFP in diets for weanling pigs may be overcome if diets are fortified with crystalline sources of Val,Trp,and(or)Ile.Methods Three hundred and twenty weanling pigs were randomly allotted to one of 10 dietary treatments in a com-pletely randomized design,with 4 pigs per pen and 8 replicate pens per treatment.A corn-soybean meal diet and 2 basal diets based on corn and 10%CFP or corn and 20%CFP were formulated.Seven additional diets were formu-lated by fortifying the basal diet with 20%CFP with Ile,Trp,Val,Ile and Val,Ile and Trp,Trp and Val,or Ile,Trp and Val.A two-phase feeding program was used,with d 1 to 14 being phase 1 and d 15 to 28 being phase 2.Fecal scores were recorded every other day.Blood samples were collected on d 14 and 28 from one pig per pen.On d 14,fecal samples were collected from one pig per pen in 3 of the 10 treatments to determine volatile fatty acids,ammonium concen-tration,and microbial protein.These pigs were also euthanized and ileal tissue was collected.Results There were no effects of dietary treatments on any of the parameters evaluated in phase 1.Inclusion of 10%or 20%CFP in diets reduced(P<0.05)final body weight on d 28,and average daily gain(ADG)and average daily feed intake(ADFI)in phase 2 and for the entire experimental period.However,pigs fed the CFP diet supplemented with Val,Ile,and Trp had final body weight,ADFI,ADG and gain to feed ratio in phase 2 and for the entire experiment that was not different from pigs fed the control diet.Fecal scores in phase 2 were reduced(P<0.05)if CFP was used.Conclusions Corn fermented protein may be included by up to 20%in diets for weanling pigs without affecting growth performance,gut heal

关 键 词：Branched-chain amino acids Corn fermented protein LEUCINE Tryptophan VALINE Weanling pigs 

分 类 号：S828.5[农业科学—畜牧学]