IgG4相关眼病诊治专家共识(2024版)  

Expert consensus on the diagnosis and treatment of immunoglobulin‑G4 related ophthalmic disease(2024 edition)

作　　者：中华医学会眼科学分会眼整形眼眶病学组 中华医学会风湿病学分会 范先群[2] 赵岩[3] 卢苇[4] 刘小伟[5] 张文[3] 周慧芳[2] Oculoplastic and Orbital Disease Group of Chinese Ophthalmological Society of Chinese Medical Association;Chinese Rheumatology Association;Fan Xianqun;Zhao Yan(不详;Department of Ophthalmology,Shanghai Ninth People′s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine,Shanghai 200011,China;Department of Rheumatology and Clinical Immunology,Peking Union Medical College Hospital,Peking Union Medical College&Chinese Academy of Medical Sciences,Beijing 100730,China)

机构地区：[1]不详 [2]上海交通大学医学院附属第九人民医院眼科,上海200011 [3]中国医学科学院,北京协和医学院,北京协和医院风湿免疫科,北京100730 [4]大连医科大学附属第二医院眼科 [5]中国医学科学院,北京协和医学院,北京协和医院眼科,北京100730

出　　处：《中华医学杂志》2024年第40期3726-3735,共10页National Medical Journal of China

摘　　要：IgG4相关眼病(IgG4‑ROD)是一种眼部免疫相关的炎症性疾病,以眼部肿块性病变合并血浆IgG4升高为主要临床表现。由于眼部组织均可受累,且可伴全身多器官、多系统发病,诊断和治疗需要多学科协作。为进一步规范中国IgG4‑ROD的诊疗方案,中华医学会眼科学分会眼整形眼眶病学组、中华医学会风湿病学分会组织该领域的眼科和风湿免疫科专家,在总结国内外临床研究结果和诊疗经验的基础上,经过共识会议制订了《IgG4相关眼病诊治专家共识(2024版)》,主要从眼部影像学、血清IgG4水平和眼部组织病理等多方面规范了IgG4‑ROD的诊断标准,并推荐了药物治疗(糖皮质激素、免疫抑制剂和生物制剂)及手术治疗的指征和方法。Immunoglobulin‑G4 related ophthalmic disease(IgG4‑ROD)is an immune‑mediated fibroin flammatory condition characterized by ocular mass lesions and elevated plasma IgG4 level.Since all the ocular tissues can be involved,and it can be accompanied by multiple organ and systemic diseases,the diagnosis and treatment require multidisciplinary collaboration.The Oculoplastic and Orbital Disease Group of Chinese Ophthalmological Society of Chinese Medical Association and the Chinese Rheumatology Association convened experts in ophthalmology,and rheumatology and immunology,and formulated"Expert consensus on the diagnosis and treatment of immunoglobulin‑G4 related ophthalmic disease(2024 edition)"for the diagnosis and treatment of IgG4‑ROD based on domestic and international studies and experience.The consensus mainly standardized the diagnostic criteria of IgG4‑ROD from the aspects of ocular imaging,serum IgG4 level and ocular histopathology,and recommended the methods and indications of drug therapy(glucocorticoids,immunosuppressants and biologics)and surgical treatment.

关 键 词：眼疾病 IgG4相关眼病 诊断 治疗 专家共识 

分 类 号：R59[医药卫生—内科学]