一例孕妇ST2型单核细胞增生李斯特菌感染的流行病学调查  

Epidemiological investigation of a maternal Listeria monocytogenes ST2 infection case

作　　者：徐伟 林云[2] 朱国英[2] 宋和佳 贾娟娟 孙炀明 XU Wei;LIN Yun;ZHU Guoying;SONG Hejia;JIA Juanjuan;SUN Yangming(Nanhu District Center for Disease Control and Prevention,Jiaxing,Zhejiang 314000,China;Jiaxing Center for Disease Control and Prevention,Jiaxing,Zhejiang 314000,China)

机构地区：[1]嘉兴市南湖区疾病预防控制中心,浙江嘉兴314000 [2]嘉兴市疾病预防控制中心,浙江嘉兴314000

出　　处：《预防医学》2025年第2期189-191,共3页China Preventive Medicine Journal

基　　金：嘉兴市科技计划项目(2023AY11037,2022AD10001)。

摘　　要：2024年9月26日,浙江省嘉兴市某市级医院报告1例孕妇单核细胞增生李斯特菌(单增李斯特菌)感染病例,为明确感染来源,嘉兴市疾病预防控制中心开展现场流行病学调查、实验室检测和处置工作。该名孕妇临床表现为发热(37.9℃),无明显诱因的阵发性腹痛且逐渐加剧,当天前往医疗机构就诊。由于胎儿宫内窘迫,当天剖宫产下1名男婴。现场流行病学调查结果显示,该孕妇平时食用水果较多,常将西瓜、葡萄等水果与生肉混放于冰箱中,且冰箱从未清洁消毒,存在交叉污染风险。孕妇羊水标本、婴儿血液标本实验室检测结果显示单增李斯特菌阳性,1份冰箱内壁涂抹标本检出单增李斯特菌阳性,菌株型别均为ST2型。孕妇进食被单增李斯特菌污染的水果可能是主要的感染来源。建议加强孕妇及其家属的食品安全教育,降低感染风险。On September 26,2024,a municipal hospital in Jiaxing City reported a maternal case of Listeria monocyto⁃genes infection.In order to clarify the source of infection,the Jiaxing Center for Disease Control and Prevention immedi⁃ately conducted the epidemiological investigation,laboratory testing and related disposal work.The case presented with fever(37.9℃),gradually intensifying paroxysmal abdominal pain without obvious cause,and went to hospital on the day of onset.Due to fetal intrauterine distress,a male infant was delivered by cesarean section on the same day.The epidemiological investigation identified that the case usually consumed fruits,often store fruits such as watermelon and grapes in the refrigerator alongside raw meat,and the refrigerator had never been cleaned or disinfected,posing a risk of cross contamination.Laboratory tests on amniotic fluid sample from the pregnant woman,infant blood sample showed positive results for Listeria monocytogenes infection.One strain of Listeria monocytogenes was detected in a smear sample from the inner wall of the refrigerator,and all the strains were ST2 type.Consuming fruits contaminated with Listeria monocytogenes may be the main source of infection.Food safety education for pregnant women and their family mem⁃bers should be strengthened to reduce the risk of infection.

关 键 词：单核细胞增生李斯特菌 孕妇 交叉污染 流行病学调查 

分 类 号：R181.3[医药卫生—流行病学]