基于CiteSpace和VOSviewer可视化分析冰片的研究热点和趋势  

Visualized analysis of research hotspot and trend of borneol based on CiteSpace and VOSviewer

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作  者:王佩茹 路大中 张萌萌 卫培峰[1] 李敏[1] 董泰玮 Wang Peiru;Lu Dazhong;Zhang Mengmeng;Wei Peifeng;Li Min;Dong Taiwei(Shaanxi University of Chinese Medicine,Xianyang Shaanxi 712046)

机构地区:[1]陕西中医药大学,陕西咸阳712046

出  处:《山西中医药大学学报》2024年第12期1299-1308,共10页Journal of Shanxi University of Chinese Medicine

基  金:国家自然基金项目(82104412);陕西省科技厅重点项目(2023-YBSF-165)。

摘  要:目的:运用文献计量学软件CiteSpace和VOSviewer探究冰片研究领域的发展现状、研究热点及趋势。方法:通过检索2003年1月1日—2023年11月23日中国知网(CNKI)数据库和Web of Science核心合集数据库中冰片研究的相关文献,手动筛选并导入CiteSpace和VOSviewer软件对其发文量、科研合作网络、关键词等进行可视化分析。结果:最终纳入中文文献1762篇,英文文献1803篇,英文文献年发文量呈现波动上升的趋势,而中文文献在2012年发文量达到峰值后开始缓慢下降,中、英文文献发文量最多的作者均是王建,中文文献发文量最多的机构是广州中医药大学,英文文献发文量最多的机构是Islamic Azad Univ,中文文献关键词分析显示在冰片研究领域主要以质量标准、含量测定、薄层色谱、质量控制等内容为热门研究方向,英文文献的关键词分析显示冰片的研究主要集中在冰片的毒性理论、药代动力学研究以及抗菌、抗氧化等药效学研究。结论:冰片在脑血管疾病治疗领域已成为目前的研究热点和重点,其调控血脑屏障发挥脑保护作用的机理还需深入研究。冰片的促渗作用机制尚不明确,其调控血脑屏障“引药上行”发挥引药入脑与现代医学的脑靶向载药系统具有紧密的联系,是未来研究的重点内容,可在开发药物新剂型中发挥重要作用。Objective:To explore the development status,research hotspots and trends in the field of borneol research by using bibliometrics software of CiteSpace and VOSviewer.Methods:Literature related to borneol research was retrieved from CNKI database and Web of Science core collection database from January 1,2003 to November 23,2023.The literature was manually screened and imported into CiteSpace and VOSviewer for visualized analysis of the number of papers,scientific research cooperation network,keywords and other aspects.Results:Finally,1762 Chinese articles and 1803 English articles were included.The annual publication volume of English articles showed a fluctuating upward trend,while the publication volume of Chinese articles began to decline slowly after reaching its peak in 2012.The author with the most published articles in both Chinese and English was Wang Jian.The institution with the largest number of Chinese articles publications was Guangzhou University of Chinese Medicine,and the institution with the largest number of English articles publications was Islamic Azad Univ.The analysis of key words in Chinese articles showed that quality standard,content determination,thin layer chromatography and quality control of borneol were popular research directions in the field of borneol research.The analysis of key words in English articles showed that the study of borneol mainly focused on the toxicity theory,pharmacokinetic study,antibacterial,antioxidant and other pharmacodynamics study.Conclusion:Borneol has become a research hotspot and focus in the field of cerebrovascular disease treatment.Its mechanism of regulating the bloodbrain barrier to play brain protection needs further study.The osmotic mechanism of borneol remains unclear.Its regulation of the blood-brain barrier by“guiding the drug to go upward”to guide the drug into the brain is closely related to current brain targeted drug delivery system,which is the focus of future research and can play an important role in the development of new drug dosag

关 键 词:冰片 文献计量学 CITESPACE VOSviewer 可视化分析 

分 类 号:R282.71[医药卫生—中药学]

 

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