血清标志物预测肩袖损伤患者伴骨质疏松预后的研究进展  

Research progress on serum markers for predicting prognosis of rotator cuff injuries

作　　者：王立乾 孙泽航(综述) 张博(审校)[2] WANG Liqian;SUN Zehang;ZHANG Bo(The Third Clinical School of Capital Medical University,Beijing 100020,China;Department of Orthope-dic,Beijing Chao Yang Hospital,Capital Medical University,Beijing 100020,China)

机构地区：[1]首都医科大学第三临床医学院,北京100020 [2]首都医科大学附属北京朝阳医院骨科,北京100020

出　　处：《医学研究与战创伤救治》2024年第12期1340-1344,共5页Journal of Medical Research & Combat Trauma Care

基　　金：首都医科大学附属北京朝阳医院临床研究孵化项目(CYFH202220)。

摘　　要：肩袖损伤伴骨质疏松患者较普通患者术后出现再撕裂的风险明显提高,临床上通常选用磁共振成像作为监测患者预后的首选方法,而关于血清标志物监测预后的研究较少。骨质疏松是肩袖损伤术后再撕裂的危险因素,并且与肩袖损伤存在共同的发病机制。在此过程中,相关的血清标志物进入血液,影响两者的发生与发展。提示血清标志物可作为监测肩袖损伤预后的指标。文章主要就骨代谢标志物、炎症标志物、氧化应激标志物和维生素D在预测肩袖损伤预后的研究进展进行综述。Patients with rotator cuff injuries accompanied by osteoporosis face a higher risk of postoperative retear compared to ordinary patients.Clinically,MRI is often the preferred method for monitoring patient prognosis,whereas research on the use of serum biomarkers for prognostic monitoring remains limited.Osteoporosis is a risk factor for postoperative retear following rotator cuff repair and shares common pathogenic mechanisms with rotator cuff injuries.During this process,relevant serum biomarkers enter the bloodstream,influencing the occurrence and development of both conditions.This suggests that serum biomarkers may serve as indicators for monitoring the prognosis of rotator cuff injuries.This article elaborates on the research progress in utilizing bone metabolism markers,inflammatory markers,oxidative stress markers,and vitamin D to predict the prognosis of rotator cuff injuries.

关 键 词：骨质疏松 肩袖损伤 血清标志物 

分 类 号：R681[医药卫生—骨科学]