药物素养与多病共存慢性病患者生活质量的关系  

Relationship between drug literacy and quality of life in patients with multiple chronic diseases

作　　者：张晓静[1] 曾琳[2] 田悦 苗翠青 冯春燕 朴玉粉[1] Zhang Xiaojing;Zeng Lin;Tian Yue;Miao Cuiqing;Feng Chunyan;Piao Yufen(Outpatient Department of Peking University Third Hospital,Beijing100191,China;Clinical Epidemiology,Peking University Third Hospital,Beijing100191,China;General Practice Department of Peking University Third Hospital,Beijing100191,China;Nursing Department of Peking University Third Hospital,Beijing100191,China)

机构地区：[1]北京大学第三医院门诊部,北京100191 [2]北京大学第三医院临床流行病学研究中心,北京100191 [3]北京大学第三医院全科医学科,北京100191 [4]北京大学第三医院护理部,北京100191

出　　处：《中华健康管理学杂志》2025年第1期14-19,共6页Chinese Journal of Health Management

基　　金：首都卫生发展专项基金(2024-2G-4097);北京大学第三医院护理科研种子基金(BYSYHL2023015)。

摘　　要：目的探讨药物素养与多病共存慢性病患者生活质量的关系。方法本研究为横断面研究,采用便利抽样法于2023年3—10月选取北京大学第三医院全科医学科260例多病共存慢性病患者,采用药物素养量表、服药依从性量表和健康调查量表(SF-36量表)对患者进行问卷调查,其中SF-36量表反映患者的生活质量(包括躯体健康和心理健康)。共发放问卷260份,收回问卷260份,其中有效问卷240份(92.3%)。采用F检验、t检验对多病共存慢性病患者的药物素养进行单因素分析,采用Pearson检验分析药物素养与服药依从性、生活质量的相关性,采用多元线性回归分析不同因素与多病共存慢性病患者服药依从性、生活质量的相关性。结果纳入分析的240例多病共存慢性病患者中,男性134例,女性106例,年龄(65.84±11.56)岁;药物素养量表得分(8.36±3.57)分;SF-36量表中的躯体健康得分(242.00±87.85)分,心理健康得分(275.67±80.29)分;服药依从性量表得分(6.22±1.93)分。多病共存慢性病患者药物素养与服药依从性(r=0.157)、心理健康(r=0.165)均呈正相关(均P<0.05)。药物素养得分(SE=2.440)、心理健康得分(SE=2.523)、无感知觉障碍(SE=2.046)、病程(SE=2.459)均与患者服药依从性呈正相关,慢性病数量(SE=-2.818)与患者服药依从性呈负相关(均P<0.05)。药物素养得分(SE=0.121)、无感知觉障碍(SE=0.399)均与患者生活质量呈正相关,慢性病数量(SE=-0.171)与患者生活质量呈负相关(均P<0.05)。结论多病共存慢性病患者的药物素养处于中等水平,药物素养与服药依从性、生活质量均呈正相关。ObjectiveTo explore the relationship between drug literacy and quality of life in patients with multiple chronic diseases.MethodsIt was a cross-sectional study.Between March and October 2023,260 patients with multiple chronic diseases from the General Medicine Department of Peking University Third Hospital were selected using a convenience sampling method.A medication literacy scale,a medication adherence scale,and a health survey scale(SF-36 scale)were used to conduct a questionnaire survey in the patients.The SF-36 scale reflected the quality of life of the patients(including physical health and mental health).A total of 260 questionnaires were distributed,260 questionnaires were returned,and 240 were effective(92.3%).Single-factor analysis of medication literacy in those patients was conducted using F-test and t-test.The correlation between medication literacy and medication adherence,as well as between medication literacy and quality of life,was analyzed using Pearson′s test.The correlation between different factors and medication adherence,as well as quality of life,in those patients was analyzed using multiple linear regression.ResultsAmong the 240 patients with multiple chronic diseases,134 were male and 106 were female,aged(65.84±11.56)years.The drug literacy scale score was(8.36±3.57)points,the SF-36 physical health score was(242.00±87.85)points,mental health score was(275.67±80.29)points,medication compliance scale score was(6.22±1.93)points.The drug literacy was positively correlated with medication compliance(r=0.157)and mental health(r=0.165)in patients with multiple chronic diseases(all P<0.05).The score of drug literacy(SE=2.440),mental health score(SE=2.523),perceptual impairment(SE=2.046)and duration of disease(SE=2.459)were positively correlated with the medication compliance of the patients,while the number of chronic diseases(SE=-2.818)was negatively correlated with the medication compliance of the patients(all P<0.05).The score of drug literacy(SE=0.121)and insensible perception disord

关 键 词：慢性病 多病共存 药物素养 服药依从性 生活质量 

分 类 号：R195[医药卫生—卫生统计学]