某地区干休所高龄老年潜在不适当用药评价及分析  

Evaluation and Analysis of Potential Inappropriate Drug Use for the Elderly in a Local Sanatorium

作　　者：柳韶真 王莹莹 赵媛媛 陈娟 吕洋 常芳芳 都艳玲 朱彦伟 蒿蕊 胡振波 Liu Shaozhen;Wang Yingying;Zhao Yuanyuna;Chen Juan;Lyu Yang;Chang Fangfang;Du Yanling;Zhu Yanwei;Hao Rui;Hu Zhenbo(The 988 th Hospital of the Joint Logistics Support Force of the Chinese People’s Liberation Army,Zhengzhou City,Henan Province 450000)

机构地区：[1]中国人民解放军联勤保障部队第九八八医院干部病房,河南郑州450000

出　　处：《黄河科技学院学报》2025年第2期11-16,共6页Journal of Huanghe S&T College

基　　金：河南医学科技攻关计划联合共建项目(LHGJ20240986)。

摘　　要：评价某地区干休所高龄老年潜在不适当用药情况,并分析影响因素。调查随访某地区干休所2023年6月至2024年6月期间116例高龄老年的基本情况及长期用药情况,基于不适当用药评估标准,以老年人不适当处方筛查工具/老年人处方遗漏筛查工具(STOPP/START)标准(第3版)对入组老人的潜在不适当用药(PIM)进行比较分析,通过多因素回归分析对相关高风险因素进行分析。共纳入116人,男女比例为8:1.2;平均年龄92.35±5.32岁;平均疾病数10.26±4.56种;长期用药平均12.5±5.22种。PIM共109例次,其中药物适应症15例次、心血管系统36例次、抗凝药物2例次、中枢神经系统32例次;潜在用药遗漏共159例次。年龄及用药数与PIM发生相关性更大,除此之外,高龄的认知障碍也影响PIM的发生,基层医疗服务及家庭应重视高龄认知障碍患者用药安全。Objective:To evaluate the potential inappropriate drug use of the elderly in a local sanatorium and analyze the influencing factors.Methods:To investigate and follow up the basic situation and long-term drug use of 116 elderly patients in a local dry house from June,2023 to June,2024,based on the evaluation criteria of inappropriate drug use,potential inappropriate medication use(PIM)among the enrolled elderly was compared using the inappropriate prescription screening tool for the elderly/prescription omission screening tool for the elderly(STOPP/START)criterion(3rd edition),and the relevant risk factors were analyzed by multivariate regression analysis.Results:A total of 116 subjects were included,with a male to female ratio of 8:1.2.Mean age 92.35±5.32 years;The mean number of diseases 10.26±4.56;The average long-term drug use was 12.5±5.22.There were 109 cases of PIM,including 15 cases of drug indications,36 cases of cardiovascular system,2 cases of anticoagulant drugs,and 32 cases of central nervous system.There were 159 cases of potential drug omission.Conclusion:Age and the number of drugs used are more correlated with the occurrence of PIM.In addition,cognitive impairment in the elderly also affects the occurrence of PIM.Primary healthcare services and families should prioritize medication safety for elderly patients with cognitive impairments.

关 键 词：高龄 老年人不适当处方筛查工具/老年人处方遗漏筛查工具标准 潜在不适当用药 

分 类 号：R969.3[医药卫生—药理学]