数字化目诊仪在高脂血症白睛目络特征与中医证候相关性研究中的应用  

Study on the correlation between the white eye veins and TCM syndromes of hyperlipidemia using digital ophthalmoscope

作　　者：吴芳颖 任璇璇[2] 吕旋 费科锋[3] 杨敏春[2] WU Fangying;REN Xuanxuan;LYU Xuan;FEI Kefeng;YANG Minchun(The Second Clinical School of Medicine,Zhejiang University of Traditional Chinese Medicine,Hangzhou 310000,Zhejiang Province,China;Department of TCM Internal Medicine,Zhejiang Hospital Affiliated to Zhejiang University School of Medicine;Information Center,Zhejiang Hospital Affiliated to Zhejiang University School of Medicine)

机构地区：[1]浙江中医药大学第二临床医学院,杭州310000 [2]浙江医院中医内科 [3]浙江医院信息中心

出　　处：《中国数字医学》2025年第2期29-33,共5页China Digital Medicine

摘　　要：目的:研究高脂血症患者的白睛目络特征,发掘其在高脂血症诊疗中的潜在价值,并探讨其与中医证候要素的相关性,以期对诊断和干预提供帮助。方法:按照诊断标准收集浙江医院中医科就诊的高脂血症患者,最终纳入痰浊阻遏型高脂血症54例及气虚型高脂血症50例,并招募非高脂血症志愿者30例。利用目诊仪采集所有受试者的眼白睛图像进行目络特征的数字化提取,并分析高脂血症的目络特征与其证候要素之间的相关性。结果:高脂血症患者“血脉”表现较健康人有统计学差异,“点”在健康人与痰浊阻遏型之间有统计学差异,“丘”在气虚型与痰浊型两组之间有统计学差异。其中,气虚型表现为显影较模糊,络脉颜色浅且多呈淡红色;络脉纤细,络脉上有瘀点、斑;痰浊阻遏型高脂血症患者白睛表面及络脉总体显影明显,络脉颜色深且多呈暗褐色;络脉偏粗、分布迂曲,络脉上有明显瘀点、斑、月晕。组间比较结果表明“丘”有统计学差异。结论:数字化目诊仪可作为临床高脂血症的无创性辅助诊断方法,有益于四诊规范化研究和提高疾病防治水平。Objective To study the ocular vascular features of white eye veins in patients with hyperlipidemia,explore its potential value in the diagnosis and treatment of hyperlipidemia,and explore its correlation with TCM syndrome elements,with a view to providing assistance in diagnosis and intervention.Methods According to the diagnostic criteria,the patients with hyperlipidemia were collected from the TCM Department of Zhejiang Hospital,54 cases of phlegm obstruction type hyperlipidemia,50 cases of Qi deficiency type hyperlipidemia and 30 nonhyperlipidemic volunteers were recruited.The white eye images of all subjects were collected by ophthalmoscope and the ocular vascular features were digitally extracted to analyze the correlation between the ocular vascular features of hyperlipidemia and its syndromic elements.Results The"blood veins"performance of hyperlipidemic patients was significantly different from that of healthy people,the"point"performance was significantly different between healthy people and phlegm obstruction type hyperlipidemic patients,the"mounds"performance was significantly different between Qi-deficiency type and phlegm obstruction type.Among them,patients with Qi deficiency type showed blurring of the surface of the white eye and the overall appearance of the veins were mostly light red in colour.The veins were thin,with petechiae and spots on the veins.Patients with phlegm-obstructed type of hyperlipidemia showed obvious appearance on the surface of the white eye and the veins,and the veins were dark brown in colour.The veins were thick and tortuous in distribution,and the veins were marked with obvious petechiae,spots and moon halos.The results of comparison between groups showed that there were significant differences between'points'and'mounds'.Conclusion Digital ophthalmoscope can be used as a non-invasive auxiliary diagnostic method for clinical hyperlipidemia,which is beneficial to the standardized study of four diagnostic methods and to improve the level of disease prevention and treatment.

关 键 词：数字化目诊仪 高脂血症 目络特征 

分 类 号：R197.3[医药卫生—卫生事业管理] R319[医药卫生—公共卫生与预防医学]