中药调控菌-肠-脑轴治疗儿童睡惊症研究进展  

Traditional Chinese Medicine Treats Pavor Nocturnus in Children by Regulating the Microbiota-Gut-Brain Axis:A Review

作　　者：赵镈凡 张禹成 杜洪喆[1] ZHAO Bofan;ZHANG Yucheng;DU Hongzhe(First Teaching Hospital of Tianjin University of Traditional Chinese Medicine,National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion,Tianjin 300381,China)

机构地区：[1]天津中医药大学第一附属医院国家中医针灸临床研究中心,天津300381

出　　处：《基层中医药》2024年第12期117-124,共8页Basic Traditional Chinese Medicine

摘　　要：儿童睡惊症是婴幼儿较为常见的一种睡眠障碍,主要表现为睡眠中突然出现的睡意朦胧的短暂惊恐状态,对儿童的生长发育产生多方负面影响。近年来我国儿童睡惊症发病率逐年上升,对儿童身心健康危害逐年增大。菌-肠-脑轴理论作为解释儿童睡眠问题的内在机制理论之一,为儿童睡惊症的诊治提供了新的思路。研究证实中药可通过调节肠道菌群改善儿童的睡眠质量,在防治儿童精神心理类疾病方面潜力巨大。本文检索了2003—2023年中国知网、万方、维普、PubMed数据库相关文献,综述中药调节菌-肠-脑轴干预儿童睡惊症的研究进展。As a common sleep disorder in children,pavor nocturnus is characterized by the rapid onset of a brief sensation of terror with unclear consciousness in sleep,leading to a variety of detrimental consequences on children's development and growth.In recent years,both the prevalence and health damage of pavor nocturnus in children have risen steadily in China.The microbiota-braingut axis hypothesis,as one of the mechanisms to explain children's sleep disorders,offers a fresh perspective on the diagnosis and management of pavor nocturnus in children.Traditional Chinese medicine can improve children's sleep quality by regulating gut microbiota and has a promising prospect for preventing and treating mental and psychological disorders in children.Based on the relevant articles published by CNKI,Wanfang Data,VIP,and PubMed from 2003 to 2023,this paper reviews the research progress in TCM treatment of pavor nocturnus in children by regulating the microbiota-gut-brainaxis.

关 键 词：肠道菌群 儿童睡惊症 儿童睡眠障碍 肠-脑轴 中药 研究进展 

分 类 号：R72[医药卫生—儿科]