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作 者:周海速[1] 朱晓珠 刘章微 陈惠南[1] 吴碎春[1] 周红卫
机构地区:[1]浙江省温州医科大学附属第一医院,325000
出 处:《浙江临床医学》2025年第1期129-131,共3页Zhejiang Clinical Medical Journal
基 金:温州医科大学附属第一医院院级护理课题(HLKY202207)。
摘 要:目的 探讨压力管理在首次接受体外受精-胚胎移植(IVF-ET)助孕女性患者中的应用效果。方法 选取2023年1月至2023年12月在本院生殖中心首次进行IVF-ET助孕的女性患者为研究对象,随机法分为观察组(79例)和对照组(78例)。对照组实施常规护理干预,观察组在常规护理基础上接受压力管理干预。比较两组患者干预前后的焦虑与压力觉知、血清及卵泡液皮质醇水平、睡眠情况及妊娠结局。结果 在干预后,观察组患者的焦虑自评量表(SAS)和压力觉知量表(PSS-14)得分均低于对照组,差异有统计学意义(P<0.05)。此外,观察组在HCG注射日的血清皮质醇水平及取卵日的卵泡液皮质醇水平均低于对照组,两组间比较差异有统计学意义(P<0.05)。观察组的睡眠状况评分、取卵日心率、血压均低于对照组,两组间比较差异有统计学意义(P<0.05)。在移植日,观察组有28例新鲜胚胎进行了移植,移植2周后23例血清HCG阳性;对照组有27例新鲜胚胎进行了移植,24例血清HCG阳性,两组间比较差异无统计学意义(χ^(2)=0.503,P=0.705)。结论 压力管理方案能有效提高IVF-ET助孕女性治疗期间应对压力的能力,降低其负面情绪和心理压力,改善睡眠状况,并可能促进临床结局的改善。Objective To explore the effect of stress management in women undergoing their first in vitro fertilization-embryo transfer(IVF-ET)assisted conception.Methods Women who underwent their first IVF-ET at our hospital's reproductive center from January 2023 to December 2023 were selected as the subjects.They were randomly divided into an experimental group(79 cases)and a control group(78 cases).The control group received routine nursing intervention,while the experimental group received stress management intervention in addition to routine nursing.The anxiety and stress perception,serum and follicular fluid cortisol levels,sleep conditions,and pregnancy outcomes before and after the intervention in both groups were compared.Results After the intervention,the experimental group's Self-Rating Anxiety Scale(SAS)and Perceived Stress Scale(PSS-14)scores were both lower than those of the control group,with statistically significant differences(P<0.05).Furthermore,the serum cortisol levels on the day of HCG injection and the follicular fluid cortisol levels on the egg retrieval day in the experimental group were both lower than those in the control group,with statistically significant differences between the two groups(P<0.05).The sleep condition scores,heart rate,and blood pressure on the egg retrieval day in the experimental group were all lower than those in the control group,with statistically significant differences between the two groups(P<0.05).On the day of embryo transfer,28 fresh embryos were transferred in the experimental group,and 23 cases were positive for serum HCG two weeks after transfer.The control group had 27 fresh embryos transferred,with 24 cases positive for serum HCG,and there was no statistically significant difference between the two groups(χ^(2)=0.503,P=0.705).Conclusion The stress management program can effectively improve the ability of women undergoing IVF-ET to cope with stress during treatment,reduce their negative emotions and psychological pressure,improve sleep conditions,and may promote
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