多层螺旋CT冠脉钙化积分与血脂、心肌酶及脂蛋白a(LPa)对诊断心梗及风险预测的意义  

The Significance of Multi-Slice Spiral CT Coronary Artery Calcification Score,Blood Lipids,Myocardial Enzymes,and Lipoprotein a(LPa)in the Diagnosis of Myocardial Infarction and Risk Prediction

作　　者：林灵 LIN Ling(Department of Radiology,Physical Examination Center of the Second People's Hospital Affiliated to Fujian University of Traditional Chinese Medicine,Fujian Fuzhou 350001)

机构地区：[1]福建中医药大学附属第二人民医院体检中心放射科,福建福州350001

出　　处：《中国医疗器械信息》2025年第2期16-18,46,共4页China Medical Device Information

摘　　要：目的:探讨与分析多层螺旋CT冠脉钙化积分与血脂、心肌酶及脂蛋白a(LPa)对诊断心梗及风险预测的意义。方法:选择2022年1月~2023年12月在本院诊治的心梗患者210例作为心梗组,选择同期体检的健康人群210例作为健康组,对两组进行多层螺旋CT冠脉钙化积分判定,检测两组的血脂、心肌酶LPa含量,随访心梗患者的预后并进行相关性分析。结果:心梗组的右冠状动脉、左冠脉主干、左前降支、左回旋支等钙化积分与总钙化积分高于健康组(P<0.05)。心梗组的血清甘油三酯、低密度脂蛋白胆固醇、总胆固醇、肌酸激酶同工酶、脂蛋白a、肌酸激酶含量高于健康组(P<0.05),血清高密度脂蛋白胆固醇含量低于健康组(P<0.05)。心梗组随访到2024年2月1日,平均(10.47±0.25)个月,发生主要心血管不良事件32例,占比15.24%。Spearman相关性分析显示主要心血管不良事件的发生与总钙化积分、甘油三酯、低密度脂蛋白胆固醇、总胆固醇、肌酸激酶同工酶、脂蛋白a、肌酸激酶、高密度脂蛋白胆固醇含量都存在相关性(P<0.05)。结论:心梗患者多伴随有多层螺旋CT冠脉钙化积分升高与血脂、心肌酶、脂蛋白a表达异常,上述指标也与心梗患者的预后状况存在相关性。Objective:To explore and analysis the significance of multi-slice spiral CT coronary artery calcification score,blood lipids,myocardial enzymes,and LPa in the diagnosis of myocardial infarction and risk prediction.Methods:210 myocardial infarction patients treated in our hospital from January 2022 to December 2023 were selected as the myocardial infarction group,and 210 healthy patients with physical examination at the same time were selected as the healthy group.The two groups were judged by multi-slice spiral CT coronary calcification points,the blood lipid and myocardial enzyme LPcontent of the two groups were detected,and the prognosis of myocardial infarction patients was followed up and analyzed.Results:In the infarction group,the calcification points and total calcification points of the right coronary artery,left main coronary artery,left anterior descending branch and left spiral branch were higher than those in the healthy group(P<0.05).Serum triglyceride,LDL cholesterol,total cholesterol,creatine kinase isoenzyme,lipoprotein a,creatine kinase were higher in healthy group(P<0.05),and serum HDL cholesterol was lower than in healthy group(P<0.05).Patients in the myocardial infarction group were followed up until February 1,2024,with an average(10.47±0.25)months.There were 32 cases of major cardiovascular adverse events,accounting for 15.24%.Spearman correlation analysis showed that the occurrence of major cardiovascular adverse events were correlated with total calcification score,triglycerides,total cholesterol,low-density lipoprotein cholesterol,lipoprotein a,creatine kinase,creatine kinase isoenzyme,and high-density lipoprotein cholesterol content(P<0.05).Conclusion:Patients with myocardial infarction are often accompanied by elevated coronary calcification scores and abnormal expression of blood lipids,myocardial enzymes,and lipoprotein a.These indicators are also correlated with the prognosis of myocardial infarction patients.

关 键 词：心肌梗死 多层螺旋CT 冠脉钙化积分 

分 类 号：R445[医药卫生—影像医学与核医学]