糖尿病相关的足感染局部抗生素治疗的价值  

The value of local antibiotics for foot infection in persons with diabetes

作　　者：张妲 肖黎 Zhang Da;Xiao Li(Department of Endocrinology,Air Force Medical Center,Beijing 100142,China)

机构地区：[1]空军特色医学中心内分泌科,北京100142

出　　处：《中华医学杂志》2024年第47期4284-4288,共5页National Medical Journal of China

摘　　要：糖尿病相关的足感染(DFI)(包括糖尿病相关的足骨髓炎),一般以全身抗生素作为治疗方案,但全身性抗生素经常被过度、过长时间使用,这使患者更容易感染多重耐药菌。局部抗生素应用对DFI患者可能有所获益。本文梳理了在DFI抗感染治疗中局部使用抗生素的优劣、种类和临床证据,指出了该领域的研究空白,并指明未来的研究方向,旨在为临床医师制定DFI抗感染方案提供参考。Diabetes‑related foot infections(DFI),including diabetes‑related foot osteomyelitis,are generally treated with systemic antibiotics.However,systemic antibiotics are often overused and administered for excessively long periods,making patients more susceptible to multidrug‑resistant bacteria.Local antibiotics may be beneficial to DFI patients.This article reviews the advantages and disadvantages,types and clinical evidence of local antibiotics in the treatment of DFI,and points out the research gaps and future research direction in this field.This article aims to provide a reference for clinicians in formulating anti‑infectious treatment plans for DFI.

关 键 词：糖尿病足 糖尿病相关的足感染 糖尿病相关的足骨髓炎 局部抗生素 

分 类 号：R587.2[医药卫生—内分泌]