术前用药对非心脏手术患者低钾血症发生的影响  

Effect of Preoperative Medication on the Occurrence of Hypokalemia in Patients Undergoing Non-cardiac Surgery

作　　者：杨小花 曾全 陈玉娟[1] YANG Xiao-hua;ZENG Quan;CHEN Yu-juan(Fujian Medical University Union Hospital,Fuzhou 350000,China)

机构地区：[1]福建医科大学附属协和医院,福建福州350000

出　　处：《海峡药学》2024年第12期104-107,共4页Strait Pharmaceutical Journal

摘　　要：目的分析术前用药对非心脏手术患者低钾血症发生的影响。方法回顾性选取2021年1月1日至2021年12月31日行非心脏手术且手术开始前有监测动脉血气的585例患者为研究对象,根据动脉血气分析结果分为低钾血症组(n=199)和非低钾血症组(n=386)。采用多因素Logistic回归分析术前发生低钾血症的影响因素。结果585例患者中术前低钾血症的发生率为34.0%。多因素Logistic回归分析发现:性别、术前准备前血钾、乳果糖、钾剂是患者术前发生低钾血症的影响因素(P<0.05)。结论使用乳果糖是术前低钾血症发生的危险因素,而使用钾剂是其保护因素。OBJECTIVE To analyze the effect of preoperative medication on the occurrence of hypokalemia in patients undergoing non-cardiac surgery.METHODS A total of 585 patients who underwent non-cardiac surgery from January 1,2021 to December 31,2021 and had arterial blood gas monitoring before the start of surgery were retrospectively selected as the study subjects.According to the results of arterial blood gas analysis,they were divided into a hypokalemia group(n=199)and a non-hypokalemia group(n=386).Multiple Logistic regression analysiswas used to analyze the influencing factors of preoperative hypokalemia.RESULTS The incidence of preoperative hypokalemia in the 585 patients was 34.0%.Multiple Logistic regression analysis showed that gender,blood potassium before preoperative preparation,lactulose and potassium agent were the influencing factors for the occurrence of preoperative hypokalemia(P<0.05).CONCLUSION The use of lactulose is a risk factor for preoperative hypokalemia,and the use of potassium is a protective factor.

关 键 词：低钾血症 围术期 动脉血气 

分 类 号：R969.4[医药卫生—药理学]