3D-Slicer辅助定位与CT定位在急性脑出血患者微创软通道引流术中的应用效果比较  

Comparison of application effects of 3D-Slicer assisted positioning and CT positioning in minimally invasive soft channel drainage in patients with acute cerebral hemorrhage

作　　者：石钟阳 SHI Zhongyang(Department of Neurosurgery of Wugang People’s Hospital,Wugang 462500 Henan,China)

机构地区：[1]舞钢市人民医院神经外科,河南舞钢462500

出　　处：《中国民康医学》2025年第3期144-146,150,共4页Medical Journal of Chinese People’s Health

摘　　要：目的:比较3D-Slicer辅助定位与CT定位在急性脑出血患者微创软通道引流术中的应用效果。方法:回顾性分析2021年5月至2022年12月该院收治的78例急性脑出血患者的临床资料,根据手术定位方法不同将其分为对照组与研究组各39例。研究组采用3D-Slicer辅助定位行微创软通道引流术治疗,对照组采用CT定位行微创软通道引流术治疗,比较两组围手术期指标(手术时间、拔管时间、住院时间、血肿吸收时间、尿激酶使用次数)水平,手术前后神经因子[中枢神经特异蛋白(S100β)、胶质纤维酸性蛋白(GFAP)、神经元特异性烯醇化酶(NSE)]水平、神经功能缺损程度[美国国立卫生研究院卒中量表(NIHSS)]评分、日常生活能力[日常生活能力(ADL)]评分,以及并发症发生率。结果:研究组手术时间、拔管时间、住院时间、血肿吸收时间均短于对照组,尿激酶使用次数少于对照组,差异有统计学意义(P<0.05);术后1周,两组GFAP、NSE、S100β水平均低于术前,且研究组低于对照组,差异有统计学意义(P<0.05);术后4、8周,两组NIHSS评分均低于术前,且研究组低于对照组,两组ADL评分均高于术前,且研究组高于对照组,差异有统计学意义(P<0.05);两组并发症发生率比较,差异无统计学意义(P>0.05)。结论:3D-Slicer辅助定位应用于急性脑出血患者微创软通道引流术中可提高患者日常生活能力评分,缩短康复进程,降低神经神功能缺损程度评分与神经因子水平,其效果优于CT定位微创软通道引流术。Objective:To compare application effects of 3D-Slicer assisted positioning and CT positioning in minimally invasive soft channel drainage in patients with acute cerebral hemorrhage.Methods:The clinical data of 78 patients with acute cerebral hemorrhage admitted to this hospital from May 2021 to December 2022 were retrospectively analyzed.According to different surgical positioning methods,they were divided into control group and study group,39 cases in each group.The study group was treated with 3D-Slicer assisted positioning for minimally invasive soft channel drainage,while the control group was treated with CT positioning for minimally invasive soft channel drainage.The perioperative indexes(operation time,extubation time,hospitalization time,hematoma absorption time,urokinase use frequency)levels,the levels of nerve factors[central nervous specific protein(S100β),glial fibrillary acidic protein(GFAP),neuron-specific enolase(NSE)]before and after the surgery,the degree of neurological deficit[National Institutes of Health stroke scale(NIHSS)]score,the activities of daily living[activity of daily living(ADL)]score,and the incidence of complications were compared between the two groups.Results:The operation time,extubation time,hospitalization time and hematoma absorption time of the study group were shorter than those of the control group,the urokinase use frequency was less than that of the control group,and the differences were statistically significant(P<0.05).At 1 week after the surgery,the levels of GFAP,NSE and S100βin the two groups were lower than those before the surgery,those in the study group were lower than those in the control group,and the differences were statistically significant(P<0.05).At 4 and 8 weeks after the surgery,the NIHSS scores of the two groups were lower than those before the surgery,and those in the study group were lower than those in the control group;the ADL scores of the two groups were higher than those before the surgery,and those in the study group were higher than those

关 键 词：急性脑出血 3D-Slicer 辅助定位 微创软通道引流术 神经因子 神经功能 日常生活能力 

分 类 号：R651.1[医药卫生—外科学]