双重免疫阻断乙型肝炎病毒母婴传播效果研究  

AN EVALUATION OF COMBINED IMMUNIZATION PREVENTING MOTHER-INFANT TRANSMISSION OF HBV

作　　者：刘声隆 周维其 颜心裕 李先惠 张育华[1] 林体淑 刘文芳[2] 刘继明[2] 余蓉[2] Liu Shenglong;Liu Wenfang(Luzhou Medical College;Chinese Academy of Medical Sciences)

机构地区：[1]泸州医学院 [2]中国医学科学院输血研究所

出　　处：《泸州医学院学报》1986年第1期8-13,共6页Journal of Luzhou Medical College

摘　　要：作者报道60例婴儿用高效价HBIG与乙肝疫苗双重免疫阻断HBV母婴传播的效果,其保护率为87.7%(除外脐血HBsAg阳性婴儿后为100%)。本文对不同免疫程序方案、HBlG效价、孕母HBeAg与HBsAg滴度等因素对免疫效果的影响作了探讨,强调制定统一免疫方案的重要性与迫切性。This paper concerns an evaluation of combeined immunization preventing mother-infant transmission of HBV with high-titer HBIG and hepatitis B Vaccine in 60 infants.The results show that its protective rate is 87.7%,not including the infants whose HBsAg of umbilicalis blood was positive.Also discussed in the paper is the influence of factors on the immune effect,such as different projections of immune proce-dure,HBIG titer,HBsAg and HBeAg in the lying-in women,The authors point out that a uniform projection of immune procedure is imperative.

关 键 词：HBV 母婴传播 HBIG 乙肝病毒疫苗 免疫接种程序 

分 类 号：R51[医药卫生—内科学]