克罗恩病肛瘘的新技术疗法研究进展  

Research progress of new technological therapies for Crohn's disease fistula

作　　者：王泰尹 孙薛亮[2] 张兆征 杜骏 张莉[3] 孙宇静 文科[2] Wang Taiyin;Sun Xueliang;Zhang Zhaozheng;Du Jun;Zhang Li;Sun Yujing;Wen Ke(Nanjing University of Chinese Medicine,Nanjing 210023,China;Suzhou TCM Hospital Affiliated to Nanjing University of Chinese Medicine,Suzhou 215000,China;Anhui University of Chinese Medicine,Hefei 230012,China)

机构地区：[1]南京中医药大学,南京210023 [2]南京中医药大学附属苏州市中医医院,苏州215000 [3]安徽中医药大学,合肥230012

出　　处：《中华炎性肠病杂志(中英文)》2024年第6期462-466,共5页Chinese Journal of Inflammatory Bowel Diseases

基　　金：2020年姑苏卫生人才培养项目(GSWS2020084);2023年苏州市临床重点病种诊疗技术专项(LCZX202322)。

摘　　要：肛周病变是克罗恩病(CD)的特征性表现,肛周病变的出现往往预示着疾病的进展,CD肛瘘则是其中最常见的病变,虽然临床上常用的生物制剂和手术能治愈部分CD肛瘘,但仍有部分CD肛瘘无法得到根治。近年来各种新技术在CD肛瘘中的应用逐渐受到临床医生的重视,特别是间充质干细胞、造血干细胞移植疗法、富血小板血浆及高压氧疗法等,本文将针对以上的新技术疗法研究进展做一综述。Perianal lesions are characteristic manifestations of Crohn's disease(CD)at the same time often herald the progression of the disease.CD fistula is one of the most common lesions,and the commonly used medications and biologics are unable to cure CD fistula.In recent years,new technology therapies have been widely used by clinicians to treat CD fistula,including platelet-rich plasma,mesenchymal stem cells,haematopoietic stem-cell transplantation and hyperbaric oxygen therapy.This article provides an overview of the progress of these non-pharmacological therapies.

关 键 词：克罗恩病 肛瘘 新技术疗法 间充质干细胞 造血干细胞移植疗法 富血小板血浆 高压氧疗法 

分 类 号：R65[医药卫生—外科学]