补阳还五汤联合银杏叶提取物注射液治疗缺血性脑卒中疗效观察  

作　　者：刘海军 郑恣峰 

机构地区：[1]河南省商丘市中医院脑病科,河南商丘476300 [2]河南省周口市中医院脑病科,河南周口466000

出　　处：《实用中医药杂志》2025年第1期5-7,共3页Journal of Practical Traditional Chinese Medicine

摘　　要：目的:观察补阳还五汤联合银杏叶提取物注射液治疗缺血性脑卒中(IS)的效果。方法:70例随机分为对照组和观察组各35例,两组均给予银杏叶提取物注射液治疗,观察组加用补阳还五汤治疗。结果:总有效率观察组高于对照组(P<0.05)。治疗后观察组BI评分较对照组高,NIHSS评分及中医证候积分较对照组低(P<0.05)。两组治疗后HBV、LBV、PV、HCT均降低,且观察组降低幅度大于对照组(P<0.05)。治疗后观察组血清NGF、BDNF水平较对照组高,而CXCL12、3-NT水平较对照组低(P<0.05)。两组不良反应发生率比较差异无统计学意义(P>0.05)。结论:补阳还五汤联合银杏叶提取物注射液治疗IS效果较好,且安全。Objective:To observe the effect of Buyang Huanwu Decoction combined with Ginkgo Biloba Extract Injection in the treatment of ischemic stroke(IS).Methods:Seventy cases were randomly divided into the control group and the observation group,with 35 cases in each group.Both groups were treated with Ginkgo Biloba Extract Injection,and the observation group were treated with Buyang Huanwu Decoction in addition.Results:The total effective rate of the observation group was higher than that of the control group(P<0.05).After treatment,the BI score of the observation group was higher than that of the control group,and the NIHSS score and TCM syndrome score were lower than those of the control group(P<0.05).After treatment,HBV,LBV,PV and HCT decreased in both groups,and the decrease in the observation group was greater than that in the control group(P<0.05).After treatment,the levels of serum NGF and BDNF in the observation group were higher than those in the control group,while the levels of CXCL12 and 3-NT were lower than those in the control group(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion:Buyang Huanwu Decoction combined with Ginkgo Biloba Extract Injection is effective and safe in the treatment of IS.

关 键 词：缺血性脑卒中 补阳还五汤 银杏叶提取物注射液 

分 类 号：R255.233[医药卫生—中医内科学]