支气管镜活检联合快速现场评估在慢性阻塞性肺疾病患者肺癌筛查中的作用  

Application of Bronchoscopy Biopsy Combined with ROSE in Lung Cancer Screening in Patients with COPD

作　　者：傅艳红 丁静 夏魁 孙伟 FU Yanhong;DING Jing;XIA Kui;SUN Wei(Department of Respiratory and Critical Care Medicine,Huaibei People's Hospital,Huaibei,Anhui 235000,China)

机构地区：[1]安徽省淮北市人民医院呼吸与危重症医学科,安徽淮北235000

出　　处：《转化医学杂志》2024年第10期1597-1600,共4页Translational Medicine Journal

基　　金：安徽省高等学校科学研究项目(2022AH051457)。

摘　　要：目的探究支气管镜活检联合快速现场评估(ROSE)技术在慢性阻塞性肺疾病(COPD)患者肺癌筛查中的作用。方法回顾性选取2022年5月至2024年5月安徽省淮北市人民医院收治的COPD合并肺癌患者80例,根据是否联合ROSE技术分为观察组(支气管镜活检+ROSE)和对照组(支气管镜活检),各40例。比较2组患者送检样本合格率及首次活检确诊情况、钳取次数、操作时间、出血量及并发症发生情况。结果观察组送检样本合格率及首次活检确诊率分别为97.50%(39/40)、92.50%(37/40),均高于对照组[分别为82.50%(33/40)、72.50%(29/40)](P<0.05)。观察组钳取次数、操作时间[分别为(6.87±1.52)次、(33.59±4.21)min]均大于对照组[分别为(5.63±0.79)次、(31.72±3.86)min](P<0.05),2组出血量比较差异无统计学意义[(4.23±0.69)mL vs(4.48±0.82)mL](P>0.05)。2组出血、气胸、咯血、胸痛各并发症发生率比较差异均无统计学意义(P>0.05)。结论在COPD合并肺癌的患者中应用支气管镜活检联合ROSE技术可提高样本的合格率和首次活检确诊率,具有良好的安全性,可推广使用。Objective To explore the role of bronchoscopy biopsy combined with rapid on-site evaluation(ROSE) technology in lung cancer screening in patients with chronic obstructive pulmonary disease(COPD).Methods A retrospective study.A total of 80 patients with COPD and lung cancer admitted to our hospital from May 2022 to May 2024 were selected.The patients were divided into observation group(bronchoscopy biopsy+ROSE)and control group(bronchoscopy biopsy)according to whether combined with ROSE technology,40 cases in each group.Compare the qualification rate of samples submitted for examination and the diagnosis of the first biopsy,the number of forceps taken,the operation time,the amount of bleeding,and the occurrence of complications between the two groups of patients.Results The qualified rate of samples submitted for inspection and the first biopsy diagnosis rate of the observation group were 97.50%(39/40)and 92.50%(37/40),respectively,which were both higher than those of the control group[82.50%(33/40)and 72.50%(29/40)](P<0.05).The number of clamps and operation time in the observation group[(6.87±1.52)times,(33.59±4.21)min]were greater than those in the control group[(5.63±0.79)times,(31.72±3.86)min](P<0.05).There was no statistically significant difference in bleeding volume between the two groups[(4.23±0.69)ml vs(4.48±0.82)ml](P>0.05).There was no statistically significant difference in the incidence of complications between the two groups(P>0.05).Conclusion The application of bronchoscopy biopsy combined with ROSE technology in patients with COPD and lung cancer can improve the sample qualification rate and the first biopsy diagnosis rate.It is safe and feasible.

关 键 词：肺疾病 慢性阻塞性 支气管镜检查 活检 快速现场评估 肺肿瘤 癌症早期检测 

分 类 号：R563.9[医药卫生—呼吸系统] R768.1[医药卫生—内科学] R734.2[医药卫生—临床医学]