单侧线状型汗孔角化症1例  

A Case of Unilateral Linear Pattern Porokeratosis of Mibelli

作　　者：张洪炜 张贤 ZHANG Hongwei;ZHANG Xian(Department of Dermatovenerology,Nantong Rici Hospital Affiliated to Yangzhou University,Nantong,Jiangsu 226010,China)

机构地区：[1]扬州大学附属南通瑞慈医院皮肤性病科,江苏南通226010

出　　处：《转化医学杂志》2024年第10期1800-1801,共2页Translational Medicine Journal

摘　　要：报告1例单侧线状汗孔角化症。患者男性,46岁,左侧上胸部、肩胛部、上肢皮疹近40年。皮肤科检查:左侧手臂见条带状分布的环形、地图形褐色斑块,界清,部分融合,斑块边缘呈堤状,中心部分皮肤轻度萎缩,其间有针头大小角质栓,皮损蔓延至上胸部及肩胛部;手背及手指伸侧部分皮损呈苔藓样变及疣状损害。取环形皮损的边缘行病理检查:镜下见周围隆起的角化过度嵴处呈充有角蛋白的凹陷,在凹窝中央见一角化不全柱,即圆锥形板层。根据患者临床表现及病理,诊断为单侧线状型汗孔角化症。予以阿维A口服治疗。To report a case of unilateral linear pattern porokeratosis of Mibelli.A 46-year-old man presented with a rash on the left upper chest,scapular region,and upper limb for nearly 40 years.Physical examination revealed ringlike and map-shaped brown plaques that were sharply demarcated and distributed in long strips on his left arm.Parts of the plaques had fused together,and the edge of the plaques was ridge-like.The central part showed mild atrophy and keratin plugs the size of pinheads.Skin lesions extended to the upper chest and scapular region.On the back of the hand and the extensor surface of the fingers,the skin lesions exhibited lichenoid and verruciform changes.Histopathological examination of the edge of the annular lesion revealed hyperkeratosis of the surrounding uplifted area,forming a concave depression filled with keratin.In the central depression,an incomplete column of keratinization(a cone-shaped multilamellar structure)was observed.Based on the clinical presentation and histopathology,the diagnosis was made as unilateral linear pattern porokeratosis of Mibelli.Oral acitretin treatment was initiated.

关 键 词：汗孔角化病 病例报告 

分 类 号：R758.68[医药卫生—皮肤病学与性病学]