某校1458名教职工甲状腺结节检出情况及相关因素分析  

Analysis of thyroid nodule detection and related factors among 1 458 faculty and staff members at a school

作　　者：吕霞霞[1] 李琳[1] 郭书含 孙惠云 史周华[1] LYU Xiaxia;LI Lin;GUO Shuhan;SUN Huiyun;SHI Zhouhua(Shandong University of Traditional Chinese Medicine,Jinan 250355,Shandong,China;Shandong Technician Institute,Jinan 250000,Shandong,China)

机构地区：[1]山东中医药大学,山东济南250355 [2]山东技师学院,山东济南250000

出　　处：《中国校医》2024年第11期822-824,834,共4页Chinese Journal of School Doctor

摘　　要：目的 了解某校教职工甲状腺结节检出情况及相关影响因素,为进一步防治甲状腺疾病提供科学依据。方法 以本校1 458名教职工为研究对象,收集一般检查、生化检查和甲状腺彩超等资料,甲状腺结节的影响因素采用logistic回归分析。结果 本校教职工甲状腺结节检出率为47.39%,其中女性为48.48%,男性为45.72%;男女甲状腺结节检出率随着年龄的增长呈上升趋势(χ_(趋势)^(2)=90.966、103.223,P均<0.001)。甲状腺结节组年龄、BMI、FBG、SBP、DBP、TC、TG、FT3、FT4水平分别为(54.90±16.13)岁、(24.33±3.57)kg/m^(2)、(5.52±1.34)mmol/L、(126.62±17.94)mmHg、(75.12±11.75)mmHg、(5.16±1.09)mmol/L、(1.50±1.13)mmol/L、(4.96±3.34)pmol/L、(16.28±4.73)pmol/L,高于非甲状腺结节组的(43.70±13.51)岁、(23.46±3.63)kg/m^(2)、(5.22±1.23)mmol/L、(122.69±16.17)mmHg、(74.13±10.58)mmHg、(5.00±0.96)mmol/L、(1.35±0.96)mmol/L、(4.94±1.40)pmol/L、(16.45±2.53)pmol/L,差异均有统计学意义(t值分别为14.469、4.596、4.416、8.475、3.484、2.888、2.707、7.140、-5.404,P均<0.05)。甲状腺结节组超重/肥胖、高血压、高血糖、高TC、高TG检出率分别为52.97%、34.59%、17.37%、30.10%、25.90%,均高于非甲状腺结节组的39.77%、19.30%、9.00%、20.60%、21.12%,差异均有统计学意义(χ^(2)值分别为25.502、41.983、22.572、17.455、4.642,P均<0.05)。logistic回归分析显示:性别、年龄、BMI、FT3为甲状腺结节的影响因素(P<0.05)。结论 本研究人群女性甲状腺结节较男性多见,年龄增长、超重/肥胖及高FT3是甲状腺结节的危险因素,高血压、高血糖、高TG、高TC可能会增加甲状腺结节的患病风险。Objective To investigate the prevalence of thyroid nodules among faculty and staff at a school and its related influencing factors,to provide a scientific basis for the prevention and treatment of thyroid diseases.Methods A total of 1458 faculty and staff members from the school were studied.Data were collected through general check-ups,biochemical tests,and thyroid color ultrasound.Logistic regression analyses were used to examine the influencing factors of thyroid nodules in the study population.Results The detection rate of thyroid nodules among the faculty and staff was 47.39%.The detection rate was 48.48%in females and 45.72%in males.The detection rates of thyroid nodules in both males and females increased with age(χ_(trend)^(2)=90.966,103.223,both P<0.001).Age,BMI,fasting blood glucose(FBG),systolic blood pressure(SBP),diastolic blood pressure(DBP),total cholesterol(TC),triglycerides(TG),free triiodothyronine(FT3),and free thyroxine(FT4)levels in the thyroid nodule group were(54.90±16.13)years,(24.33±3.57)kg/m^(2),(5.52±1.34)mmol/L,(126.62±17.94)mmHg,(75.12±11.75)mmHg,(5.16±1.09)mmol/L,(1.50±1.13)mmol/L,(4.96±3.34)pmol/L,and(16.28±4.73)pmol/L,respectively.These results were higher than those in the non-thyroid nodule group:(43.70±13.51)years,(23.46±3.63)kg/m^(2),(5.22±1.23)mmol/L,(122.69±16.17)mmHg,(74.13±10.58)mmHg,(5.00±0.96)mmol/L,(1.35±0.96)mmol/L,(4.94±1.40)pmol/L,and(16.45±2.53)pmol/L(t values were 14.469,4.596,4.416,8.475,3.484,2.888,2.707,7.140,and-5.404,all P<0.05).Detection rates of overweight and/or obesity,hypertension,high blood glucose,high total cholesterol(TC),and high triglycerides(TG)in the thyroid nodule group were 52.97%,34.59%,17.37%,30.10%,and 25.90%,respectively,all higher than those in the non-thyroid nodule group(39.77%,19.30%,9.00%,20.60%,and 21.12%;χ^(2) values were 25.502,41.983,22.572,17.455,and 4.642,all significant at P<0.05).Logistic regression analysis showed that gender,age,BMI,and FT3 were influencing factors for thyroid nodules(P<0.05).Conclusions In

关 键 词：院校 甲状腺结节 危险因素 

分 类 号：R446[医药卫生—诊断学]