多普勒及弹性成像评价重度主动脉瓣狭窄患者TAVI术后肾脏情况  

Evaluation of Renal Blood Flow in Patient Underwent TAVI with Severe Aortic Stenosis by Doppler Ultrasound and Shear Wave Elastography

作　　者：孙薇 刘楠楠 徐凯 李洋 李金佩 牟成铭 Sun Wei;Liu Nannan;Xu Kai;Li Yang;Li Jinpei;Mou Chengming(Postgraduate Joint Training Base of General Hospital of Northern Theater Command of Jinzhou Medical University,Shenyang 110016,China;Institute of Cardiovascular Diseases of PLA,General Hospital of Northern Theater Command,Shenyang 110016,China)

机构地区：[1]锦州医科大学北部战区总医院研究生联合培养基地,沈阳市110016 [2]北部战区总医院全军心血管病研究所,沈阳市110016

出　　处：《中国超声医学杂志》2025年第1期36-38,共3页Chinese Journal of Ultrasound in Medicine

基　　金：2022年度国家重点研发计划“常见多发病防治研究”重点专项项目(No.2022YFC2503403)。

摘　　要：目的应用多普勒及剪切波弹性成像(SWE)评价重度主动脉瓣狭窄(AS)患者经导管主动脉瓣置换术(TAVI)后肾脏血流动力学等相关情况。方法初次行TAVI的重度AS患者97例,术前及术后1个月测量肾脏大小、皮质厚度,各级动脉收缩期最高流速(PSV)、舒张期最低流速(EDV)、阻力指数(RI)、搏动指数(PI)及肾实质弹性模量值(E),收集临床生化指标血肌酐、胱抑素及尿素,比较各参数及生化指标术前术后差异。结果TAVI术后肾脏各级动脉PSV、EDV升高,RI及PI下降,肾实质E降低,差异具有统计学意义(P<0.05)。结论TAVI术后肾脏血流灌注增加,多普勒及SWE对TAVI术后肾脏血流灌注评价有诊断价值。Objective To evaluate the renal hemodynamics and related conditions in patients with severe aortic stenosis(AS)after transcatheter aortic valve implantation(TAVI)by Doppler ultrasound and shear wave elastography(SWE).Methods A total of 97 patients with severe AS underwent TAVI for the first time were collected,and the kidney size,cortical thickness,arterial peak systolic velocity(PSV),end diastolic velocity(EDV),resistance index(RI),pulsatility index(PI),and renal parenchymal elastic modulus(E)before and 1 month after surgery were measured.The clinical biochemical parameters of serum creatinine,cystatin C,and urea before and after surgery were also collected and compared.Results After TAVI,renal arterial PSV and EDV at all branches were increased,RI and PI were decreased,and renal parenchymal elastic modulus value was decreased,all with a statistically significant difference(P<0.05).Conclusions Renal blood perfusion increases after TAVI,Doppler ultrasound and SWE have diagnostic value in evaluating renal blood perfusion after TAVI.

关 键 词：剪切波弹性成像 肾脏 主动脉瓣狭窄 经导管主动脉瓣置换术 

分 类 号：R65[医药卫生—外科学]