纳米纤维素功能化生物医用水凝胶的研究进展  

Research progress of nanocellulose functionalized biomedical hydrogels

作　　者：陈亚君 朱洋洋 孟琎旻 杨振铭 赵兵 李国辉 CHEN Yajun;ZHU Yangyang;MENG Jinmin;YANG Zhenming;ZHAO Bing;LI Guohui(School of Textile Clothing and Art Media,Suzhou Institute of Trade&Commerce,Suzhou 215009,China;School of Biotechnology,Jiangnan University,Wuxi 214122,China)

机构地区：[1]苏州经贸职业技术学院纺织服装与艺术传媒学院,江苏苏州215009 [2]江南大学生物工程学院,江苏无锡214122

出　　处：《印染》2025年第2期76-81,共6页China Dyeing and Finishing

基　　金：江苏省自然科学基金资助项目(BK20221247);苏州经贸职业技术学院院级科研项目(仿生纳米纤维复合凝胶的构建及医用性能研究YJ-ZK2403)。

摘　　要：纳米纤维素因其来源丰富、易于改性、力学性能优异、安全无毒以及可生物降解等特性,为生物医用水凝胶的功能化开辟了新机遇。目前,基于纳米纤维素的功能化水凝胶在生物医学领域的研究中备受关注。介绍了纳米纤维素的分子结构和制备方法,探讨了纳米纤维素对水凝胶功能化的设计策略,阐明纳米纤维素在功能化水凝胶中的作用机制,总结了纳米纤维素基功能化水凝胶在药物递送、创伤敷料以及组织支架等生物医用领域的最新研究进展,最后对纳米纤维素基水凝胶在生物医学领域的发展机遇和挑战进行了简要概括。Nanocellulose creates a new opportunity for the functionalization of biomedical hydrogels owing to its natural abundance,tailorable surface chemistry,superior mechanical property,biocompatibility and biodegradability.Currently,nanocellulose-based functional hydrogels are in the limelight of extensive researchers from biomedical field.Herein,the molecular structure and preparation methods of nanocellulose are introduced.The design strategy of nanocellulose-functionalized hydrogels and the corresponding mechanism of nanocellulose are discussed and highlighted.And the latest research progress of nanocellulose-based functional hydrogels in biomedical fields such as drug delivery,wound dressings and tissue scaffolds is summarized.Finally,both opportunities and challenges of the nanocellulose-based hydrogels in the biomedical field are briefly summarized.

关 键 词：纳米纤维素 功能化 水凝胶 生物医用 

分 类 号：TS106[轻工技术与工程—纺织工程] TS210.4[轻工技术与工程—纺织科学与工程]